Our understanding of the still unfolding severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) pandemic would have been extremely limited without the study of the …

The COVID-19 pandemic has been accompanied by SARS-CoV-2 evolution and
emergence of viral variants that have far exceeded initial expectations. Five major variants of …

Abstract The SARS-CoV-2 Omicron BA. 1 variant emerged in 2021 and has multiple
mutations in its spike protein. Here we show that the spike protein of Omicron has a higher …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of
concern evades antibody-mediated immunity that comes from vaccination or infection with …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages carry
distinct spike mutations resulting in escape from antibodies induced by previous infection or …

The Delta variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
outcompeted previously prevalent variants and become a dominant strain worldwide. We …

Although infections among vaccinated individuals lead to milder COVID-19 symptoms
relative to those in unvaccinated subjects, the specificity and durability of antibody …

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of
concern comprises several sublineages, with BA. 2 and BA. 2.12. 1 having replaced the …

Currently circulating SARS-CoV-2 variants have acquired convergent mutations at hot spots
in the receptor-binding domain (RBD) of the spike protein. The effects of these mutations on …

The recently emerged SARS-CoV-2 Omicron variant encodes 37 amino acid substitutions in
the spike protein, 15 of which are in the receptor-binding domain (RBD), thereby raising …