Bioactive Compounds, Pharmacological Actions, and Pharmacokinetics of Genus Acacia
Plants are a promising source of bioactive compounds that can be used to tackle many
emerging diseases both infectious and non-infectious. Among different plants, Acacia is a …
emerging diseases both infectious and non-infectious. Among different plants, Acacia is a …
Dark side of cancer therapy: cancer treatment-induced cardiopulmonary inflammation, fibrosis, and immune modulation
E Boopathi, C Thangavel - International Journal of Molecular Sciences, 2021 - mdpi.com
Advancements in cancer therapy increased the cancer free survival rates and reduced the
malignant related deaths. Therapeutic options for patients with thoracic cancers include …
malignant related deaths. Therapeutic options for patients with thoracic cancers include …
Azithromycin mitigates cisplatin-induced lung oxidative stress, inflammation and necroptosis by upregulating SIRT1, PPARγ, and Nrf2/HO-1 signaling
EHM Hassanein, GA Sayed, AM Alzoghaibi… - Pharmaceuticals, 2022 - mdpi.com
Acute lung injury (ALI) is one of the adverse effects of the antineoplastic agent cisplatin
(CIS). Oxidative stress, inflammation, and necroptosis are linked to the emergence of lung …
(CIS). Oxidative stress, inflammation, and necroptosis are linked to the emergence of lung …
Effect of bisphenol F, an analog of bisphenol A, on the reproductive functions of male rats
Abstract Objective Bisphenol A (BPA) is a monomer primarily used in the production of
polycarbonate plastic and epoxy resins. Bisphenol F (BPF) is apparently the main BPA …
polycarbonate plastic and epoxy resins. Bisphenol F (BPF) is apparently the main BPA …
The Effect of Taxifolin on Cisplatin‐Induced Pulmonary Damage in Rats: A Biochemical and Histopathological Evaluation
The effect of taxifolin on cisplatin‐induced oxidative pulmonary damage was investigated
biochemically and histopathologically in male albino Wistar rats. There were four groups …
biochemically and histopathologically in male albino Wistar rats. There were four groups …
Molecular docking, pharmacokinetic studies, and in vivo pharmacological study of indole derivative 2-(5-methoxy-2-methyl-1H-indole-3-yl)-N′-[(E)-(3-nitrophenyl) …
Cisplatin is an efficient anticancer drug against various types of cancers however, its usage
involves side effects. We investigated the mechanisms of action of indole derivative, 2-(5 …
involves side effects. We investigated the mechanisms of action of indole derivative, 2-(5 …
Acacia hydaspica R. Parker ethyl-acetate extract abrogates cisplatin-induced nephrotoxicity by targeting ROS and inflammatory cytokines
Cisplatin (CisPT) is a chemotherapeutic drug that outcomes in adverse effects. In this study,
we examined the effect of A. hydaspica ethyl acetate extract (AHE) in an animal model of …
we examined the effect of A. hydaspica ethyl acetate extract (AHE) in an animal model of …
Phytochemical analysis and Evaluation of hepatoprotective effect of Maytenus royleanus leaves extract against anti-tuberculosis drug induced liver injury in mice
Abstract Background Myrin®-p Forte is an anti-tuberclosis agent that can cause hepatic
injuries in clinical settings. Maytenus royleanus (Celastraceae) is a medicinal plant …
injuries in clinical settings. Maytenus royleanus (Celastraceae) is a medicinal plant …
Isorhamnetin: a flavonoid, attenuated doxorubicin-induced testicular injury via regulation of steroidogenic enzymes and apoptotic signaling gene expression in male …
Background Male reproductive damage is one of the most adverse side effects of
doxorubicin (DOX). Isorhamnetin is a natural flavonoid, which displays remarkable …
doxorubicin (DOX). Isorhamnetin is a natural flavonoid, which displays remarkable …
Fish collagen peptides protect against cisplatin-induced cytotoxicity and oxidative injury by inhibiting MAPK signaling pathways in mouse thymic epithelial cells
WH Song, HY Kim, YS Lim, SY Hwang, C Lee, DY Lee… - Marine Drugs, 2022 - mdpi.com
Thymic epithelial cells (TECs) account for the most abundant and dominant stromal
component of the thymus, where T cells mature. Oxidative-or cytotoxic-stress associated …
component of the thymus, where T cells mature. Oxidative-or cytotoxic-stress associated …