AI-powered therapeutic target discovery

FW Pun, IV Ozerov, A Zhavoronkov - Trends in Pharmacological Sciences, 2023 - cell.com
Disease modeling and target identification are the most crucial initial steps in drug
discovery, and influence the probability of success at every step of drug development …

Machine learning for synthetic data generation: a review

Y Lu, M Shen, H Wang, X Wang, C van Rechem… - arXiv preprint arXiv …, 2023 - arxiv.org
Machine learning heavily relies on data, but real-world applications often encounter various
data-related issues. These include data of poor quality, insufficient data points leading to …

A multifaceted benchmarking of synthetic electronic health record generation models

C Yan, Y Yan, Z Wan, Z Zhang, L Omberg… - Nature …, 2022 - nature.com
Synthetic health data have the potential to mitigate privacy concerns in supporting
biomedical research and healthcare applications. Modern approaches for data generation …

[HTML][HTML] Racial underrepresentation in dermatological datasets leads to biased machine learning models and inequitable healthcare

G Kleinberg, MJ Diaz, S Batchu… - Journal of biomed …, 2022 - ncbi.nlm.nih.gov
Objective: Clinical applications of machine learning are promising as a tool to improve
patient outcomes through assisting diagnoses, treatment, and analyzing risk factors for …

Balancing the picture: Debiasing vision-language datasets with synthetic contrast sets

B Smith, M Farinha, SM Hall, HR Kirk… - arXiv preprint arXiv …, 2023 - arxiv.org
Vision-language models are growing in popularity and public visibility to generate, edit, and
caption images at scale; but their outputs can perpetuate and amplify societal biases …

An ontology for fairness metrics

JS Franklin, K Bhanot, M Ghalwash… - Proceedings of the …, 2022 - dl.acm.org
Recent research has revealed that many machine-learning models and the datasets they
are trained on suffer from various forms of bias, and a large number of different fairness …

AI fairness in data management and analytics: A review on challenges, methodologies and applications

P Chen, L Wu, L Wang - Applied sciences, 2023 - mdpi.com
This article provides a comprehensive overview of the fairness issues in artificial intelligence
(AI) systems, delving into its background, definition, and development process. The article …

[HTML][HTML] Generating synthetic clinical data that capture class imbalanced distributions with generative adversarial networks: Example using antiretroviral therapy for …

I Nicholas, H Kuo, F Garcia, A Sönnerborg… - Journal of Biomedical …, 2023 - Elsevier
Objective: Clinical data's confidential nature often limits the development of machine
learning models in healthcare. Generative adversarial networks (GANs) can synthesise …

[HTML][HTML] The need to strengthen the evaluation of the impact of Artificial Intelligence-based decision support systems on healthcare provision

K Cresswell, M Rigby, F Magrabi, P Scott, J Brender… - Health policy, 2023 - Elsevier
Despite the renewed interest in Artificial Intelligence-based clinical decision support systems
(AI-CDS), there is still a lack of empirical evidence supporting their effectiveness. This …

FoGGAN: Generating realistic Parkinson's disease freezing of gait data using GANs

N Peppes, P Tsakanikas, E Daskalakis, T Alexakis… - Sensors, 2023 - mdpi.com
Data scarcity in the healthcare domain is a major drawback for most state-of-the-art
technologies engaging artificial intelligence. The unavailability of quality data due to both …