Chlorine is one of the most common atoms present in small-molecule drugs beyond carbon,
hydrogen, nitrogen, and oxygen. There are currently more than 250 FDA-approved chlorine …

Pyrazolo [1, 5-a] pyrimidine (PP) derivatives are an enormous family of N-heterocyclic
compounds that possess a high impact in medicinal chemistry and have attracted a great …

Reviewing the advancements in malaria treatment, the emergence of triazole hybrid
compounds stands out as a groundbreaking development. Combining the advantages of …

Malaria is the fifth most lethal parasitic infection in the world. Antimalarial medications have
played a crucial role in preventing and eradicating malaria. Numerous heterocyclic moieties …

Amongst heterocyclic compounds, quinoline and its derivatives are advantaged scaffolds
that appear as a significant assembly motif for developing new drug entities. Aminoquinoline …

Currently, selective COX-2 inhibitors are used as a novel alternative approach in the course
of pain management due to their reduced adverse that generally occur after COX-1 …

Malaria, that ancient infectious disease is considered a great health problem due to its
highly infectious and mortality rates. The more harmful kind of malaria is Plasmodium …

The novel series of coumarin derivatives have been synthesized, and the chemical
structures of the compounds have been elucidated by 1 H NMR, 13 C NMR, and LC/MS-IT …

Although we have at our disposal relatively low-cost drugs that can be prescribed for the
treatment of malaria, the prevalence of resistant strains of the causative parasite has …

Herein, we report a catalyst-free synthesis of C3-halo substituted bicyclo [1.1. 1]
pentylamines under mild conditions. The reaction involves the use of sodium hypohalites …