Iron metabolism in aging and age-related diseases

Y Tian, Y Tian, Z Yuan, Y Zeng, S Wang, X Fan… - International journal of …, 2022 - mdpi.com
Iron is a trace metal element necessary to maintain life and is also involved in a variety of
biological processes. Aging refers to the natural life process in which the physiological …

Copper homeostasis and cuproptosis in gynecological disorders: Pathogenic insights and therapeutic implications

Y Lin, M Yuan, G Wang - Journal of Trace Elements in Medicine and …, 2024 - Elsevier
This review comprehensively explores the complex role of copper homeostasis in female
reproductive system diseases. As an essential trace element, copper plays a crucial role in …

Serum copper concentration reflect inflammatory activation in the complex coronary artery disease–A pilot study

T Urbanowicz, A Hanć, A Olasińska-Wiśniewska… - Journal of Trace …, 2022 - Elsevier
Introduction Coronary artery disease possess inflammatory background related to enzymatic
processes with trace elements involvements as co-factors. The aim of the study was to …

Remodeling of imbalanced extracellular matrix homeostasis for reversal of pancreatic fibrosis

L Qi, H Han, MM Han, Y Sun, L Xing, HL Jiang… - Biomaterials, 2023 - Elsevier
Pancreatic fibrosis is mainly manifested by imbalance in extracellular matrix (ECM)
homeostasis due to excessive deposition of collagen in pancreas by activated pancreatic …

[HTML][HTML] Novel LncRNA LINC02936 Suppresses Ferroptosis and Promotes Tumor Progression by Interacting with SIX1/CP Axis in Endometrial Cancer

Z Zhang, B Li, Z Wang, L Yang, J Peng… - … Journal of Biological …, 2024 - ncbi.nlm.nih.gov
Endometrial cancer (EC) is a prevalent gynecological malignancy, and metabolic disorders
are among its most significant risk factors. Abnormal iron metabolism is associated with the …

Integrating Proteomics and Lipidomics for Evaluating the Risk of Breast Cancer Progression: A Pilot Study

NL Starodubtseva, AO Tokareva, VV Rodionov… - Biomedicines, 2023 - mdpi.com
Metastasis is a serious and often life-threatening condition, representing the leading cause
of death among women with breast cancer (BC). Although the current clinical classification …

Serum Level of Ceruloplasmin, Angiotensin-Converting Enzyme and Transferrin as Markers of Severity in SARS-CoV-2 Infection in Patients with Type 2 Diabetes

PA Reștea, Ș Țigan, LG Vicaș, L Fritea, E Marian… - Microbiology …, 2023 - mdpi.com
The aim of this study was to analyze other possible new markers of severity, at hospital
admission, that can be assessed in patients with type 2 diabetes and a SARS-CoV-2 (severe …

Evaluation the role of cuproptosis-related genes in the pathogenesis, diagnosis and molecular subtypes identification of atherosclerosis

M Wang, L Cheng, Q Xiang, Z Gao, Y Ding, H Xie… - Heliyon, 2023 - cell.com
Background At present, the pathogenesis of atherosclerosis has not been fully elucidated,
and the diagnosis and treatment face great challenges. Cuproptosis is a novel cell death …

Ceruloplasmin is associated with the infiltration of immune cells and acts as a prognostic biomarker in patients suffering from glioma

M Jia, T Dong, Y Cheng, F Rong, J Zhang… - Frontiers in …, 2023 - frontiersin.org
Glioma is regarded as a prevalent form of cancer that affects the Central Nervous System
(CNS), with an aggressive growth pattern and a low clinical cure rate. Despite the …

Abnormalities in copper status associated with an elevated risk of Parkinson's phenotype development

MN Karpenko, ZM Muruzheva, EY Ilyechova… - Antioxidants, 2023 - mdpi.com
In the last 15 years, among the many reasons given for the development of idiopathic forms
of Parkinson's disease (PD), copper imbalance has been identified as a factor, and PD is …