Engineered nucleic acids and methods of use thereof

Engineered nucleic acids encoding a modified erythropoietin and their expression

JP Schrum, NB Afeyan, GJ Sieczkiewicz… - US Patent …, 2014 - Google Patents
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被引用次数：418 相关文章 所有 4 个版本

Terminally modified RNA

T Chakraborty, S Bancel, SG Hoge, A Roy… - US Patent …, 2017 - Google Patents
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被引用次数：310 相关文章 所有 4 个版本

Modified polynucleotides for the production of biologics and proteins associated with human disease

S Bancel, T Chakraborty, A De Fougerolles… - US Patent …, 2015 - Google Patents
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被引用次数：287 相关文章 所有 4 个版本

Modified polynucleotides for the production of secreted proteins

T Chakraborty, A De Fougerolles - US Patent 9,192,651, 2015 - Google Patents
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被引用次数：283 相关文章 所有 4 个版本

Engineered nucleic acids and methods of use thereof

S Bancel, JP Schrum, A Aristarkhov - US Patent 9,464,124, 2016 - Google Patents
A61K48/0075—Medicinal preparations containing genetic material which is inserted into
cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of …
被引用次数：224 相关文章 所有 4 个版本

In vivo production of proteins

S Bancel, T Chakraborty, A De Fougerolles… - US Patent …, 2015 - Google Patents
2013-03-19 Assigned to modeRNA Therapeutics reassignment modeRNA Therapeutics
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被引用次数：225 相关文章 所有 4 个版本

Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins

T Chakraborty, A De Fougerolles - US Patent 9,303,079, 2016 - Google Patents
2013-03-19 Assigned to modeRNA Therapeutics reassignment modeRNA Therapeutics
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …
被引用次数：220 相关文章 所有 4 个版本

Nucleic acid vaccines

G Ciaramella, A Bouchon, EYC Huang - US Patent 10,022,435, 2018 - Google Patents
US10022435B2 - Nucleic acid vaccines - Google Patents US10022435B2 - Nucleic acid
vaccines - Google Patents Nucleic acid vaccines Download PDF Info Publication number …
被引用次数：166 相关文章 所有 4 个版本

Nucleic acid vaccines

G Ciaramella, A Bouchon, EYC Huang - US Patent 9,872,900, 2018 - Google Patents
US9872900B2 - Nucleic acid vaccines - Google Patents US9872900B2 - Nucleic acid vaccines
- Google Patents Nucleic acid vaccines Download PDF Info Publication number US9872900B2 …
被引用次数：165 相关文章 所有 4 个版本

Compositions and methods of altering cholesterol levels

SG Hoge, A De Fougerolles, JL Ellsworth - US Patent 8,980,864, 2015 - Google Patents
2014-03-21 Assigned to MODERNA THERAPEUTICS, INC. reassignment MODERNA
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被引用次数：202 相关文章 所有 4 个版本