Amplification is the primary mode of gene-by-sex interaction in complex human traits
Sex differences in complex traits are suspected to be in part due to widespread gene-by-sex
interactions (GxSex), but empirical evidence has been elusive. Here, we infer the mixture of …
interactions (GxSex), but empirical evidence has been elusive. Here, we infer the mixture of …
Tradeoffs in modeling context dependency in complex trait genetics
Genetic effects on complex traits may depend on context, such as age, sex, environmental
exposures or social settings. However, it is often unclear if the extent of context dependency …
exposures or social settings. However, it is often unclear if the extent of context dependency …
Genetic insights: mapping sex-specific loci in Siamese cobra (Naja kaouthia) sheds light on the putative sex determining region
The location of female-specific/linked loci identified in Siamese cobra (Naja kaouthia)
previously has been determined through in silico chromosome mapping of the Indian cobra …
previously has been determined through in silico chromosome mapping of the Indian cobra …
[PDF][PDF] Finding the functional consequences of genetic risk loci on gene expression and DNA methylation by integrating contextual information
W Casazza - 2023 - open.library.ubc.ca
The majority of genetic loci that influence complex traits are non-coding. Roughly half of
these loci affect gene expression in one or more tissues, despite making up less than 10% of …
these loci affect gene expression in one or more tissues, despite making up less than 10% of …