Epigenetics in NAFLD/NASH: Targets and therapy

N Sodum, G Kumar, SL Bojja, N Kumar… - Pharmacological …, 2021 - Elsevier
Recently non-alcoholic fatty liver disease (NAFLD) has grabbed considerable scientific
attention, owing to its rapid increase in prevalence worldwide and growing burden on end …

[HTML][HTML] Regulatory mechanisms of the early phase of white adipocyte differentiation: An overview

M Audano, S Pedretti, D Caruso, M Crestani… - Cellular and molecular …, 2022 - Springer
The adipose organ comprises two main fat depots termed white and brown adipose tissues.
Adipogenesis is a process leading to newly differentiated adipocytes starting from precursor …

[HTML][HTML] Metabolic and epigenetic regulation by estrogen in adipocytes

JI Bjune, PP Strømland, RÅ Jersin… - Frontiers in …, 2022 - frontiersin.org
Sex hormones contribute to differences between males and females in body fat distribution
and associated disease risk. Higher concentrations of estrogens are associated with a more …

[HTML][HTML] Cannabidiol regulates apoptosis and autophagy in inflammation and cancer: A review

Z Fu, PY Zhao, XP Yang, H Li, SD Hu, YX Xu… - Frontiers in …, 2023 - frontiersin.org
Cannabidiol (CBD) is a terpenoid naturally found in plants. The purified compound is used
in the treatment of mental disorders because of its antidepressive, anxiolytic, and …

[HTML][HTML] Butyrate and obesity: Current research status and future prospect

K Peng, W Dong, T Luo, H Tang, W Zhu… - Frontiers in …, 2023 - frontiersin.org
Over the past few decades, increasing prevalence of obesity caused an enormous medical,
social, and economic burden. As the sixth most important risk factor contributing to the …

[HTML][HTML] Management of obesity and obesity-related disorders: from stem cells and epigenetics to its treatment

S Cruciani, AP Delitala, ML Cossu, C Ventura… - International Journal of …, 2023 - mdpi.com
Obesity is a complex worldwide disease, characterized by an abnormal or excessive fat
accumulation. The onset of this pathology is generally linked to a complex network of …

LncIMF2 promotes adipogenesis in porcine intramuscular preadipocyte through sponging MiR-217

XD Yi, ZZ He, TT Tian, ZY Kou, WJ Pang - Animal Biotechnology, 2023 - Taylor & Francis
Intramuscular fat is positively related to meat quality including tenderness, flavor, and
juiciness. Long noncoding RNA (LncRNA) plays a vital role in regulating adipogenesis …

[HTML][HTML] Altered H3K4me3 profile at the TFAM promoter causes mitochondrial alterations in preadipocytes from first-degree relatives of type 2 diabetics

M Longo, F Zatterale, R Spinelli, J Naderi, L Parrillo… - Clinical …, 2023 - Springer
Background First-degree relatives of type 2 diabetics (FDR) exhibit a high risk of developing
type 2 diabetes (T2D) and feature subcutaneous adipocyte hypertrophy, independent of …

The evolutionary impact and influence of oestrogens on adipose tissue structure and function

O Bardhi, BF Palmer, DJ Clegg - … Transactions of the …, 2023 - royalsocietypublishing.org
Oestrogens are sex steroid hormones that have gained prominence over the years owing to
their crucial roles in human health and reproduction functions which have been preserved …

[HTML][HTML] m6A demethylase FTO regulate CTNNB1 to promote adipogenesis of chicken preadipocyte

K Li, W Huang, Z Wang, Q Nie - Journal of Animal Science and …, 2022 - Springer
Abstract Background N6-methyladenosine (m6A) is an abundant post-transcriptional RNA
modification that affects various biological processes. The fat mass and obesity-associated …