The regulatory role of antisense lncRNAs in cancer

B Liu, W Xiang, J Liu, J Tang, J Wang, B Liu… - Cancer cell …, 2021 - Springer
Antisense long non-coding RNAs (antisense lncRNAs), transcribed from the opposite strand
of genes with either protein coding or non-coding function, were reported recently to play a …

A long non-coding RNA with important roles in the carcinogenesis

S Ghafouri-Fard, A Askari, BM Hussen… - Frontiers in Cell and …, 2022 - frontiersin.org
Long non-coding RNAs are demonstrated to contribute to carcinogenesis. TMPO Antisense
RNA 1 (TMPO-AS1) is an example of lncRNAs with crucial roles in this process. This lncRNA …

The long transcript of lncRNA TMPO-AS1 promotes bone metastases of prostate cancer by regulating the CSNK2A1/DDX3X complex in Wnt/β-catenin signaling

M Wang, C Yin, Z Wu, X Wang, Q Lin, X Jiang… - Cell Death …, 2023 - nature.com
The second most common male cancer is prostate cancer (PCa), which has a high tendency
for bone metastasis. Long non-coding RNAs, including TMPO-AS1, play a crucial role in …

LncRNA TUG1 promotes pulmonary fibrosis progression via up-regulating CDC27 and activating PI3K/Akt/mTOR pathway

F Qi, ZD Lv, WD Huang, SC Wei, XM Liu, WD Song - Epigenetics, 2023 - Taylor & Francis
Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease with an unclear
pathogenesis. This study aimed to elucidate the function and potential mechanisms of TUG1 …

Single-cell sequencing reveals effects of chemotherapy on the immune landscape and TCR/BCR clonal expansion in a relapsed ovarian cancer patient

Y Ren, R Li, H Feng, J Xie, L Gao, S Chu, Y Li… - Frontiers in …, 2022 - frontiersin.org
Cancer recurrence and chemoresistance are the leading causes of death in high-grade
serous ovarian cancer (HGSOC) patients. However, the unique role of the immune …

The landscape of human p53‐regulated long non‐coding RNAs reveals critical host gene co‐regulation

M Fischer, K Riege, S Hoffmann - Molecular Oncology, 2023 - Wiley Online Library
The role of long non‐coding RNAs (lncRNAs) in p53‐mediated tumor suppression has
become increasingly appreciated in the past decade. Thus, the identification of p53 …

Hsa-miR-195-5p inhibits autophagy and gemcitabine resistance of lung adenocarcinoma cells via E2F7/CEP55

L Fu, Z Li, Y Wu, T Zhu, Z Ma, L Dong, J Ding… - Biochemical …, 2023 - Springer
Lung adenocarcinoma (LUAD) is a common malignancy. Many studies have shown that
LUAD is resistant to gemcitabine chemotherapy, resulting in poor treatment outcomes in …

The emerging role of thymopoietin-antisense RNA 1 as long noncoding RNA in the pathogenesis of human cancers

Q Zheng, J Jia, Z Zhou, Q Chu, W Lian… - DNA and Cell …, 2021 - liebertpub.com
Long noncoding RNAs (lncRNAs) play essential roles in the occurrence and development of
multiple human cancers. An accumulating body of researches have investigated …

Deciphering the Oncogenic Landscape: Unveiling the Molecular Machinery and Clinical Significance of LncRNA TMPO-AS1 in Human Cancers

F Ajila, M Alwan, ZH Athab, JB Shaier… - … -Research and Practice, 2024 - Elsevier
The in-depth exploration of long non-coding RNAs (lncRNAs) reveals their pivotal and
diverse roles in various disorders, particularly cancer. Within this intricate landscape …

LncRNA TMPO-AS1 suppresses the maturation of miR-335-5p to participate in polycystic ovary syndrome

F Hou, J Li, J Peng, Z Teng, J Feng, W Xia - Journal of Ovarian Research, 2021 - Springer
Background TMPO-AS1 is a recently characterized oncogenic lncRNA in ovarian cancer. Its
role in other ovary diseases is unknown. This study explored its role in polycystic ovary …