Molecular imaging findings on acute and long-term effects of COVID-19 on the brain: a systematic review

PT Meyer, S Hellwig, G Blazhenets… - Journal of Nuclear …, 2022 - Soc Nuclear Med
Molecular imaging techniques such as PET and SPECT have been used to shed light on
how coronavirus disease 2019 (COVID-19) affects the human brain. We provide a …

Viruses, parkinsonism and Parkinson's disease: The past, present and future

V Leta, D Urso, L Batzu, YH Lau, D Mathew… - Journal of Neural …, 2022 - Springer
Parkinsonism secondary to viral infections is not an uncommon occurrence and has been
brought under the spotlight with the spread of severe acute respiratory syndrome …

ACE2 expression in rat brain: Implications for COVID-19 associated neurological manifestations

VS Hernández, MA Zetter, EC Guerra… - Experimental …, 2021 - Elsevier
We examined cell type-specific expression and distribution of rat brain angiotensin-
converting enzyme 2 (ACE2), the receptor for SARS-CoV-2, in the rodent brain. ACE2 is …

SARS-CoV-2 spike protein S1 domain accelerates α-synuclein phosphorylation and aggregation in cellular models of synucleinopathy

J Wang, L Dai, M Deng, T Xiao, Z Zhang… - Molecular …, 2024 - Springer
The 2019 novel coronavirus disease (COVID-19) is an infectious disease that began to
spread globally since 2019. Some COVID-19 patients have neurological complications …

Can SARS-CoV-2 infection lead to neurodegeneration and Parkinson's disease?

L Krey, MK Huber, GU Höglinger, F Wegner - Brain Sciences, 2021 - mdpi.com
The SARS-CoV-2 pandemic has affected the daily life of the worldwide population since
2020. Links between the newly discovered viral infection and the pathogenesis of …

COVID‐19 Infection Enhances Susceptibility to Oxidative Stress–Induced Parkinsonism

RJ Smeyne, JB Eells, D Chatterjee, M Byrne… - Movement …, 2022 - Wiley Online Library
Background Viral induction of neurological syndromes has been a concern since
parkinsonian‐like features were observed in patients diagnosed with encephalitis lethargica …

SARS‐CoV‐2, aging, and Post‐COVID‐19 neurodegeneration

MJ Strong - Journal of Neurochemistry, 2023 - Wiley Online Library
As the world continues to experience the effects of SARS‐CoV‐2, there is evidence to
suggest that the sequelae of viral infection (the post‐COVID‐19 condition; PCC) at both an …

COVID-19 and parkinsonism: a critical appraisal

F Cavallieri, V Fioravanti, F Bove, E Del Prete, S Meoni… - Biomolecules, 2022 - mdpi.com
A few cases of parkinsonism linked to COVID-19 infection have been reported so far, raising
the possibility of a post-viral parkinsonian syndrome. The objective of this review is to …

Coronavirus disease 2019 and related parkinsonism: the clinical evidence thus far

I Boura, KR Chaudhuri - Movement disorders clinical practice, 2022 - Wiley Online Library
ABSTRACT Background The Coronavirus disease 2019 (Covid‐19) pandemic has fueled
both research and speculation, as to whether it could be a “perfect storm” for a post‐Covid …

Diagnostic and therapeutic agents that target alpha-synuclein in Parkinson's disease

CK Nwabufo, OP Aigbogun - Journal of neurology, 2022 - Springer
The development of disease-modifying drugs and differential diagnostic agents is an urgent
medical need in Parkinson's disease. Despite the complex pathophysiological pathway, the …