Structure and mutagenesis of the DNA modification-dependent restriction endonuclease AspBHI
The modification-dependent restriction endonuclease AspBHI recognizes 5-methylcytosine
(5mC) in the double-strand DNA sequence context of (C/T)(C/G)(5mC) N (C/G)(N= any …
(5mC) in the double-strand DNA sequence context of (C/T)(C/G)(5mC) N (C/G)(N= any …
Structure-based deep mining reveals first-time annotations for 46 percent of the dark annotation space of the 9,671-member superproteome of the nucleocytoplasmic …
Y Mirzakhanyan, PD Gershon - Journal of virology, 2020 - Am Soc Microbiol
We conducted an exhaustive search for three-dimensional structural homologs to the
proteins of 20 key phylogenetically distinct nucleocytoplasmic DNA viruses (NCLDV) …
proteins of 20 key phylogenetically distinct nucleocytoplasmic DNA viruses (NCLDV) …
[HTML][HTML] Half a century after their discovery: Structural insights into exonuclease and annealase proteins catalyzing recombineering
Recombineering is an essential tool for molecular biologists, allowing for the facile and
efficient manipulation of bacterial genomes directly in cells without the need for costly and …
efficient manipulation of bacterial genomes directly in cells without the need for costly and …
Bioinformatics analysis of bacterial annexins–putative ancestral relatives of eukaryotic annexins
PK Kodavali, M Dudkiewicz, S Pikuła, K Pawłowski - PloS one, 2014 - journals.plos.org
Annexins are Ca2+-binding, membrane-interacting proteins, widespread among eukaryotes,
consisting usually of four structurally similar repeated domains. It is accepted that vertebrate …
consisting usually of four structurally similar repeated domains. It is accepted that vertebrate …
The draft genome of strain cCpun from biting midges confirms insect Cardinium are not a monophyletic group and reveals a novel gene family expansion in a …
Background It is estimated that 13% of arthropod species carry the heritable symbiont
Cardinium hertigii. 16S rRNA and gyrB sequence divides this species into at least four …
Cardinium hertigii. 16S rRNA and gyrB sequence divides this species into at least four …
Long-B prokaryotic Argonaute systems employ various effectors to confer immunity via abortive infection
X Song, S Lei, S Liu, Y Liu, P Fu, Z Zeng, K Yang… - bioRxiv, 2023 - biorxiv.org
Argonaute proteins (Agos) bind short nucleic acids as guides and are directed by them to
recognize target complementary nucleic acids. Prokaryotic Agos (pAgos) are extremely …
recognize target complementary nucleic acids. Prokaryotic Agos (pAgos) are extremely …
Structural features of Chi recognition in AddAB with implications for RecBCD
M Wilkinson, DB Wigley - Cell Cycle, 2014 - Taylor & Francis
AddAB and RecBCD-type helicase-nuclease complexes control the first stage of bacterial
homologous recombination (HR)–the resection of double strand DNA breaks. A switch in the …
homologous recombination (HR)–the resection of double strand DNA breaks. A switch in the …
Endonuclease domain of non-LTR retrotransposons: loss-of-function mutants and modeling of the R2Bm endonuclease
A Govindaraju, JD Cortez, B Reveal… - Nucleic acids …, 2016 - academic.oup.com
Non-LTR retrotransposons are an important class of mobile elements that insert into host
DNA by target-primed reverse transcription (TPRT). Non-LTR retrotransposons must bind to …
DNA by target-primed reverse transcription (TPRT). Non-LTR retrotransposons must bind to …
Novel recA-Independent Horizontal Gene Transfer in Escherichia coli K-12
AW Kingston, C Roussel-Rossin, C Dupont… - PloS one, 2015 - journals.plos.org
In bacteria, mechanisms that incorporate DNA into a genome without strand-transfer
proteins such as RecA play a major role in generating novelty by horizontal gene transfer …
proteins such as RecA play a major role in generating novelty by horizontal gene transfer …
A betabaculovirus encoding a gp64 homolog
Background A betabaculovirus (DisaGV) was isolated from Diatraea saccharalis
(Lepidoptera: Crambidae), one of the most important insect pests of the sugarcane and other …
(Lepidoptera: Crambidae), one of the most important insect pests of the sugarcane and other …