A reaction–diffusion within-host HIV model with cell-to-cell transmission

X Ren, Y Tian, L Liu, X Liu - Journal of mathematical biology, 2018 - Springer
In this paper, a reaction–diffusion within-host HIV model is proposed. It incorporates cell
mobility, spatial heterogeneity and cell-to-cell transmission, which depends on the diffusion …

A modular framework for multiscale, multicellular, spatiotemporal modeling of acute primary viral infection and immune response in epithelial tissues and its …

TJ Sego, JO Aponte-Serrano… - PLoS computational …, 2020 - journals.plos.org
Simulations of tissue-specific effects of primary acute viral infections like COVID-19 are
essential for understanding disease outcomes and optimizing therapies. Such simulations …

Iterative community-driven development of a SARS-CoV-2 tissue simulator

M Getz, Y Wang, G An, M Asthana, A Becker… - BioRxiv, 2020 - biorxiv.org
The 2019 novel coronavirus, SARS-CoV-2, is an emerging pathogen of critical significance
to international public health. Knowledge of the interplay between molecular-scale virus …

Dynamics of IFN-β responses during respiratory viral infection. Insights for therapeutic strategies

A Watson, CM Spalluto, C McCrae… - American journal of …, 2020 - atsjournals.org
Rationale: Viral infections are major drivers of exacerbations and clinical burden in patients
with asthma and chronic obstructive pulmonary disease (COPD). IFN-β is a key component …

[HTML][HTML] Traveling waves in delayed reaction-diffusion equations in biology

S Trofimchuk, V Volpert - Mathematical Biosciences and …, 2020 - aimspress.com
This paper represents a literature review on traveling waves described by delayed
reactiondiffusion (RD, for short) equations. It begins with the presentation of different types of …

Current Perspectives in Antiviral Research

OA Tarasova - International Journal of Molecular Sciences, 2023 - mdpi.com
Studies on virus–host interactions are of high significance for a number of reasons. First,
comparing the molecular mechanisms of virus–host interactions allows researchers to …

Modelling the dynamics of virus infection and immune response in space and time

G Bocharov, A Meyerhans, N Bessonov… - … Journal of Parallel …, 2019 - Taylor & Francis
Spreading of viral infection in the tissues such as lymph nodes or spleen depends on virus
multiplication in the host cells, their transport and on the immune response. Reaction …

Baicalin mitigates nephropathogenic infectious bronchitis virus infection-induced spleen injury via modulation of mitophagy and macrophage polarization in Hy-Line …

G Tian, C Huang, Z Li, Z Lu, C Feng, Y Zhuang… - Veterinary …, 2023 - Elsevier
Nephropathogenic infectious bronchitis virus (NIBV) infections continue to pose a significant
hazard in the poultry industry. Baicalin is a natural flavonoid that has been reported to have …

Infection spreading in cell culture as a reaction-diffusion wave

LA Mahiout, N Bessonov, B Kazmierczak… - ESAIM: Mathematical …, 2022 - esaim-m2an.org
Infection spreading in cell culture occurs due to virus replication in infected cells and its
random motion in the extracellular space. Multiplicity of infection experiments in cell cultures …

[HTML][HTML] Delay reaction-diffusion equation for infection dynamics

N Bessonov, G Bocharov, TM Touaoula… - … Dynamical Systems-B, 2019 - aimsciences.org
Nonlinear dynamics of a reaction-diffusion equation with delay is studied with numerical
simulations in 1D and 2D cases. Homogeneous in space solutions can manifest time …