Efficacy and safety of tocilizumab and baricitinib among patients hospitalized for COVID-19: a systematic review and meta-analysis
J Zhang, X Fan, X Zhang, F Jiang, Y Wu… - Frontiers in …, 2023 - frontiersin.org
Introduction: Tocilizumab and baricitinib are recommended treatment options for COVID-19
patients with hyperinflammatory response; however, there is a lack of systematic review …
patients with hyperinflammatory response; however, there is a lack of systematic review …
JAK-STAT signaling in inflammation and stress-related diseases: Implications for therapeutic interventions
A Sarapultsev, E Gusev, M Komelkova, I Utepova… - Molecular …, 2023 - Springer
The Janus kinase-signal transducer and transcription activator pathway (JAK-STAT) serves
as a cornerstone in cellular signaling, regulating physiological and pathological processes …
as a cornerstone in cellular signaling, regulating physiological and pathological processes …
High-valent metal-oxo species heterogeneous activation making use of MoS2 in a novel Electro-Fenton System: pH-independent catalytic environment and nonradical …
High-valent metal-oxo (HVMO) species emerge as promising reactive species for
decontamination owing to its long and stable life expectancy. Nevertheless, it is challenging …
decontamination owing to its long and stable life expectancy. Nevertheless, it is challenging …
Integrating network pharmacology with molecular docking to rationalize the ethnomedicinal use of Alchornea laxiflora (Benth.) Pax & K. Hoffm. for efficient treatment of …
NK Jain, M Tailang, B Chandrasekaran… - Frontiers in …, 2024 - frontiersin.org
Background: Alchornea laxiflora (Benth.) Pax & K. Hoffm.(A. laxiflora) has been indicated in
traditional medicine to treat depression. However, scientific rationalization is still lacking …
traditional medicine to treat depression. However, scientific rationalization is still lacking …
Parechovirus infection in human brain organoids: host innate inflammatory response and not neuro-infectivity correlates to neurologic disease
PE Capendale, I García-Rodríguez, AT Ambikan… - Nature …, 2024 - nature.com
Picornaviruses are a leading cause of central nervous system (CNS) infections. While
genotypes such as parechovirus A3 (PeV-A3) and echovirus 11 (E11) can elicit severe …
genotypes such as parechovirus A3 (PeV-A3) and echovirus 11 (E11) can elicit severe …
Agranulocytosis and secondary infection related to JAK inhibitors and IL-6 receptor blockers: a disproportionality analysis using the US Food and drug administration …
C Wei, W Yin, T Hu, J Zhang, H Dan… - Frontiers in Pharmacology, 2024 - frontiersin.org
Background: Given that the fight against coronavirus disease 2019 (COVID-19) is not over,
we aimed to explore the occurrence of agranulocytosis and infectious complications in …
we aimed to explore the occurrence of agranulocytosis and infectious complications in …
Signaling pathways and potential therapeutic targets in acute respiratory distress syndrome (ARDS)
Q Huang, Y Le, S Li, Y Bian - Respiratory Research, 2024 - Springer
Acute respiratory distress syndrome (ARDS) is a common condition associated with critically
ill patients, characterized by bilateral chest radiographical opacities with refractory …
ill patients, characterized by bilateral chest radiographical opacities with refractory …
[HTML][HTML] Agranulocytosis and secondary infection related to JAK inhibitors and IL-6 receptor blockers: a disproportionality analysis using the US Food and drug …
C Wei, W Yin, T Hu, J Zhang, H Dan… - Frontiers in Pharmacology, 2024 - frontiersin.org
Background: Given that the fight against coronavirus disease 2019 (COVID-19) is not over,
we aimed to explore the occurrence of agranulocytosis and infectious complications in …
we aimed to explore the occurrence of agranulocytosis and infectious complications in …
Cyclooxygenase-2/prostaglandin E2 pathway regulates infectious bronchitis virus replication in avian macrophages
ME Mahmoud, M Farooq, IM Isham… - Journal of General …, 2024 - microbiologyresearch.org
Infectious bronchitis virus (IBV) is a significant respiratory pathogen that affects chickens
worldwide. As an avian coronavirus, IBV leads to productive infection in chicken …
worldwide. As an avian coronavirus, IBV leads to productive infection in chicken …
Clinical Outcomes among Hospitalized COVID-19 Patients Who Received Baricitinib or Tocilizumab in Addition to Standard of Care
CP Walker, NP Hurlock, S Deb - Diseases, 2024 - mdpi.com
COVID-19 infection is caused by the novel severe acute respiratory syndrome coronavirus 2
(SAR-CoV-2). This novel virus has transformed into different resistant variants (eg, omicron; …
(SAR-CoV-2). This novel virus has transformed into different resistant variants (eg, omicron; …