Epithelial barrier hypothesis: effect of the external exposome on the microbiome and epithelial barriers in allergic disease

Z Celebi Sozener, B Ozdel Ozturk, P Cerci, M Turk… - Allergy, 2022 - Wiley Online Library
Environmental exposure plays a major role in the development of allergic diseases. The
exposome can be classified into internal (eg, aging, hormones, and metabolic processes) …

Oxidative stress in the skin: Impact and related protection

J Chen, Y Liu, Z Zhao, J Qiu - International Journal of Cosmetic …, 2021 - Wiley Online Library
Skin, our first interface to the external environment, is subjected to oxidative stress caused
by a variety of factors such as solar ultraviolet, infrared and visible light, environmental …

Malondialdehyde as a potential oxidative stress marker for allergy-oriented diseases: an update

R Cordiano, M Di Gioacchino, R Mangifesta… - Molecules, 2023 - mdpi.com
Malondialdehyde (MDA) is a compound that is derived from the peroxidation of
polyunsaturated fatty acids. It has been used as a biomarker to measure oxidative stress in …

Oxidative stress in biological systems and its relation with pathophysiological functions: the effect of physical activity on cellular redox homeostasis

J Kruk, HY Aboul-Enein, A Kładna… - Free radical …, 2019 - Taylor & Francis
The body of evidence from the past three decades demonstrates that oxidative stress can be
involved in several diseases. This study aims to summarise the current state of knowledge …

Impact of air pollution on atopic dermatitis: a comprehensive review

Z Pan, Y Dai, N Akar-Ghibril, J Simpson, H Ren… - Clinical Reviews in …, 2023 - Springer
Air pollution is associated with multiple health problems worldwide, contributing to increased
morbidity and mortality. Atopic dermatitis (AD) is a common allergic disease, and increasing …

Regulation of skin barrier function via competition between AHR axis versus IL-13/IL-4‒JAK‒STAT6/STAT3 axis: pathogenic and therapeutic implications in atopic …

M Furue - Journal of Clinical Medicine, 2020 - mdpi.com
Atopic dermatitis (AD) is characterized by skin inflammation, barrier dysfunction, and chronic
pruritus. As the anti-interleukin-4 (IL-4) receptor α antibody dupilumab improves all three …

Oxidative stress and atopic dermatitis

L Bertino, F Guarneri, SP Cannavò, M Casciaro… - Antioxidants, 2020 - mdpi.com
Atopic dermatitis is a common chronic/chronically relapsing inflammatory skin disease, with
increasing worldwide prevalence. Etiopathogenesis is complex and multifactorial, with a mix …

Therapeutic hydrogel patch to treat atopic dermatitis by regulating oxidative stress

YE Kim, SW Choi, MK Kim, TL Nguyen, J Kim - Nano letters, 2022 - ACS Publications
Atopic dermatitis (AD) is a chronic inflammatory disease associated with unbalanced
immune responses in skin tissue. Although steroid drugs and antihistamines are generally …

Overcome the barriers of the skin: exosome therapy

GH Yang, YB Lee, D Kang, E Choi, Y Nam, KH Lee… - Biomaterials …, 2021 - Springer
Exosomes are nano-sized cargos with a lipid bilayer structure carrying diverse biomolecules
including lipids, proteins, and nucleic acids. These small vesicles are secreted by most types …

Effect of oral administration of a mixture of probiotic strains on SCORAD index and use of topical steroids in young patients with moderate atopic dermatitis: a …

V Navarro-López, A Ramírez-Boscá… - JAMA …, 2018 - jamanetwork.com
Importance Oral intake of new probiotic formulations may improve the course of atopic
dermatitis (AD) in a young population. Objective To determine whether a mixture of oral …