Exploring the immunogenic properties of SARS-CoV-2 structural proteins: PAMP: TLR signaling in the mediation of the neuroinflammatory and neurologic sequelae of …

MG Frank, M Fleshner, SF Maier - Brain, Behavior, and Immunity, 2023 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) produces an array of
neurologic and neuropsychiatric symptoms in the acute and post-acute phase of infection …

[HTML][HTML] Clinical approach to post-acute sequelae after COVID-19 infection and vaccination

N Hulscher, BC Procter, C Wynn, PA McCullough - Cureus, 2023 - ncbi.nlm.nih.gov
The spike protein of SARS-CoV-2 has been found to exhibit pathogenic characteristics and
be a possible cause of post-acute sequelae after SARS-CoV-2 infection or COVID-19 …

[HTML][HTML] On fine particulate matter and COVID-19 spread and severity: An in vitro toxicological plausible mechanism

S Marchetti, M Gualtieri, A Pozzer, J Lelieveld… - Environment …, 2023 - Elsevier
COVID-19 pandemic had a significant impact on global public health. The spread of the
disease was related to the high transmissibility of SARS-CoV-2 virus but incidence and …

[HTML][HTML] The novelty of mRNA viral vaccines and potential harms: a scoping review

MTJ Halma, J Rose, T Lawrie - J, 2023 - mdpi.com
Pharmacovigilance databases are showing evidence of injury in the context of the modified
COVID-19 mRNA products. According to recent publications, adverse event reports linked to …

Ox-inflammasome involvement in neuroinflammation

A Vallese, V Cordone, A Pecorelli, G Valacchi - Free Radical Biology and …, 2023 - Elsevier
Neuroinflammation plays a crucial role in the onset and the progression of several
neuropathologies, from neurodegenerative disorders to migraine, from Rett syndrome to …

[HTML][HTML] Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike Protein S1 Induces Methylglyoxal-Derived Hydroimidazolone/Receptor for …

D Manfredelli, M Pariano, C Costantini… - International Journal of …, 2023 - mdpi.com
The pathogenesis of coronavirus disease 2019 (COVID-19) is associated with a
hyperinflammatory response. The mechanisms of SARS-CoV-2-induced inflammation are …

[HTML][HTML] Concern about the effectiveness of mRNA vaccination technology and its long-term safety: Potential interference on miRNA machinery

G Stati, P Amerio, M Nubile, S Sancilio, F Rossi… - International Journal of …, 2023 - mdpi.com
After the outbreak of the pandemic due to COVID-19 infection, several vaccines were
developed on short timelines to counteract the public health crisis. To allow the …

[HTML][HTML] COVID-19 and Gastrointestinal Tract: From Pathophysiology to Clinical Manifestations

F Vernia, H Ashktorab, N Cesaro, S Monaco, S Faenza… - Medicina, 2023 - mdpi.com
Background: Since its first report in Wuhan, China, in December 2019, COVID-19 has
become a pandemic, affecting millions of people worldwide. Although the virus primarily …

ACE2 expression and spike S1 protein‐mediated immune responses in oral mucosal cells

M Akagi, K Ohta, S Fukada, M Sakuma… - Oral …, 2024 - Wiley Online Library
Objectives ACE2, known as a host receptor involved with SARS‐CoV‐2 infection, binds to
viral spike proteins for host cell entry. However, details regarding its induction and function …

[HTML][HTML] Distinct Effects of Respiratory Viral Infection Models on miR-149-5p, IL-6 and p63 Expression in BEAS-2B and A549 Epithelial Cells

N Shahdab, C Ward, PM Hansbro, S Cummings… - Cells, 2024 - mdpi.com
Respiratory viruses cause airway inflammation, resulting in epithelial injury and repair.
miRNAs, including miR-149-5p, regulate different pathological conditions. We aimed to …