The wide and rapid spread of the COVID-19 pandemic has placed an unanticipated burden
on the global healthcare sector. This necessitated a swift response from the international …

Introduction The impact of different doses of dexamethasone on outcomes from acute
COVID-19 pneumonia is unknown. Methods We performed a systematic review and meta …

Background The optimal dose of dexamethasone for severe/critical COVID‐19 is uncertain.
We compared higher versus standard doses of dexamethasone in adults with COVID‐19 …

Drug repurposing (or repositioning) is the process of finding new therapeutic uses for drugs
already approved by drug regulatory authorities (eg, the Food and Drug Administration …

Background Low-dose corticosteroids have been shown to reduce mortality for hypoxic
COVID-19 patients requiring oxygen or ventilatory support (non-invasive mechanical …

The COVID-19 pandemic has posed a major challenge to healthcare systems globally.
Millions of people have been infected, and millions of deaths have been reported worldwide …

Introduction: The acute respiratory distress syndrome (ARDS), secondary to viral
pneumonitis, is one of the main causes of high mortality in patients with COVID-19 (novel …

Background Currently, some meta-analyses on COVID-19 have suggested that
glucocorticoids use can reduce the mortality rate of COVID-19 patients, utilization rate of …

More than 3 years after its first appearance, severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) is still among the most troublesome respiratory viruses and the coronavirus …

Idiopathic pulmonary fibrosis (IPF) is a debilitating, life-threatening irreversible lung disease
characterized by the excessive accumulation of fibrotic tissue in the lungs, impairing their …