Maintaining a healthy gut environment is a prerequisite for sustainable animal production.
The gut plays a key role in the digestion and absorption of nutrients and constitutes an initial …

Recent evidence provides support for involvement of the microbiota-gut-brain axis in
Parkinson's disease (PD) pathogenesis. We propose that a pro-inflammatory intestinal …

Effective drug delivery is important in the treatment of various biomedical conditions, ranging
from autoimmune disorders to cancer and bacterial infections. Nanostructured systems can …

The colonic mucosa provides a vital defensive barrier separating the body from the microbial
populations residing in the intestinal lumen. Indeed, growing evidence shows that loss of …

It has been more than 100 years since Paul Ehrlich reported that various water-soluble dyes
injected into the circulation did not enter the brain. Since Ehrlich's first experiments, only a …

Airway epithelial cells form a barrier to the outside world and are at the front line of mucosal
immunity. Epithelial apical junctional complexes are multiprotein subunits that promote cell …

Defects in intestinal barrier function are associated with diseases of the gastrointestinal (GI)
tract. There is growing evidence that increases in intestinal permeability plays a pathogenic …

Loss of the blood-retinal barrier (BRB) integrity and subsequent damage to the
neurovascular unit in the retina are the underlying reasons for diabetic retinopathy (DR) …

The intestinal immune system is exposed to a mixture of foreign antigens from diet,
commensal flora and potential pathogens. Understanding how pathogen-specific immunity …

Heat stress (HS) compromises the yield and quality of poultry products and endangers the
sustainability of the poultry industry. Despite being homeothermic, chickens, especially fast …