RNA-based devices controlling gene expression bear great promise for synthetic biology, as
they offer many advantages such as short response times and light metabolic burden …

Nucleic acid aptamers are an expandable toolkit of sensors and regulators. To employ
aptamer regulators within nonequilibrium molecular networks, the aptamer–ligand …

Precise control over the nucleation, growth, and termination of self-assembly processes is a
fundamental tool for controlling product yield and assembly dynamics. Mechanisms for …

Life is sustained by a variety of cyclic processes such as cell division, muscle contraction,
and neuron firing. The periodic signals powering these processes often direct a variety of …

We provide necessary and sufficient structural conditions for multistationarity and
oscillations in aggregate monotone systems, defined as the interconnection of stable …

Biomolecular circuits with two distinct and stable steady states have been identified as
essential components in a wide range of biological networks, with a variety of mechanisms …

A dynamical network is comprised of a finite number of subsystems, each having its own
dynamics, which interact according to a given interconnection topology. Dynamical networks …

We design a new negative feedback molecular oscillator and study its properties analytically
and numerically. This oscillator is composed of two synthetic genes interconnected through …

The CRISPR/Cas-based genome editing system has provided a powerful tool for control of
gene activity within cells. Here, we model an experimentally plausible architecture …

We model an experimentally plausible implementation of a synthetic RNA-based
biochemical toggle switch proposed in previous work by the authors. We show that the …