[HTML][HTML] The RANK/RANKL/OPG system and tumor bone metastasis: Potential mechanisms and therapeutic strategies

Y Zhang, J Liang, P Liu, Q Wang, L Liu… - Frontiers in …, 2022 - frontiersin.org
With the markedly increased diagnosis and incidence of cancer in the population, tumor
bone metastasis has become a frequent event in tumor patients. Healthy bone integrity is …

Osteomalacia is not a single disease

L Cianferotti - International Journal of Molecular Sciences, 2022 - mdpi.com
Among bone-material qualities, mineralization is pivotal in conferring stiffness and
toughness to the bone. Osteomalacia, a disease ensuing from inadequate mineralization of …

[HTML][HTML] Constructions of ROS-responsive titanium-hydroxyapatite implant for mesenchymal stem cell recruitment in peri-implant space and bone formation in …

M Chen, Y Sun, Y Hou, Z Luo, M Li, Y Wei, M Chen… - Bioactive materials, 2022 - Elsevier
To solve the issue of unsatisfactory recruitment of mesenchymal stem cells (MSCs) around
implant in osteoporotic fractures, we fabricated a ROS-responsive system on titanium …

Smart, biomimetic periosteum created from the cerium (III, IV) oxide-mineralized eggshell membrane

QQ Wan, K Jiao, YX Ma, B Gao, Z Mu… - … Applied Materials & …, 2022 - ACS Publications
The periosteum orchestrates the microenvironment of bone regeneration, including
facilitating local neuro-vascularization and regulating immune responses. To mimic the role …

Burosumab and Dental Abscesses in Children With X Linked Hypophosphatemia

M Gadion, A Hervé, J Herrou… - Journal of Bone and …, 2022 - academic.oup.com
ABSTRACT X linked hypophosphatemia (XLH) is a rare genetic disorder that disrupts
skeletal and dental mineralization. In addition to rickets in children, XLH patients also have …

A seminal perspective on the role of chondroitin sulfate in biomineralization

J Hao, Q Wan, Z Mu, J Gu, W Yu, W Qin, Y Li… - Carbohydrate …, 2023 - Elsevier
Chondroitin sulfate (CS) is an important extracellular matrix component of mineralized
tissues. It participates in biomineralization, osteoblast differentiation and promotes bone …

Trojan-horse mineralization of trigger factor to impregnate non-woven alginate fabrics for enhanced hemostatic efficacy

C Liu, C Liu, Z Shi, Z Li, X Wang, F Huang - Carbohydrate Polymers, 2023 - Elsevier
Uncontrolled hemorrhage remains a leading cause of mortality after trauma. This work
describes a facile mineralization strategy for enhancing hemostatic efficacy of alginate non …

Single Cell RNA Sequencing Reveals Critical Functions of Mkx in Periodontal Ligament Homeostasis

K Takada, T Chiba, T Miyazaki, L Yagasaki… - Frontiers in Cell and …, 2022 - frontiersin.org
The periodontal ligament (PDL) comprises a fibrous tissue that connects teeth to alveolar
bone and is essential for periodontal function. The transcription factor mohawk homeobox …

Nature-inspired unconventional approaches to develop 3D bioceramic scaffolds with enhanced regenerative ability

A Ruffini, M Sandri, M Dapporto, E Campodoni… - Biomedicines, 2021 - mdpi.com
Material science is a relevant discipline in support of regenerative medicine. Indeed, tissue
regeneration requires the use of scaffolds able to guide and sustain the natural cell …

A biomineralized Prussian blue nanotherapeutic for enhanced cancer photothermal therapy

D Zhong, Y Wang, F Xie, S Chen, X Yang… - Journal of Materials …, 2022 - pubs.rsc.org
Photothermal therapy is a promising tumor ablation technique that converts light into heat
energy to kill cancer cells. Prussian blue (PB), a biocompatible photothermal reagent, has …