Emerging application of nanomedicine-based therapy in acute respiratory distress syndrome

Y Xu, L Lv, Q Wang, Q Yao, L Kou, H Zhang - Colloids and Surfaces B …, 2024 - Elsevier
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are serious lung
injuries caused by various factors, leading to increased permeability of the alveolar-capillary …

[HTML][HTML] N-acetylcysteine reduces severity and mortality in COVID-19 patients: A systematic review and meta-analysis

MS Alam, MN Hasan, Z Maowa, F Khatun… - Journal of advanced …, 2023 - ncbi.nlm.nih.gov
Objectives: Recent clinical studies suggest that oxidative stress is one of the key players in
the pathogenesis of coronavirus disease 2019 (COVID-19), and N-acetylcysteine (NAC), a …

N-acetyl cysteine restores the diminished activity of the antioxidant enzymatic system caused by SARS-CoV-2 infection: Preliminary findings

ME Soto, L Manzano-Pech, A Palacios-Chavarría… - Pharmaceuticals, 2023 - mdpi.com
SARS-CoV-2 infects type II pneumocytes and disrupts redox homeostasis by overproducing
reactive oxygen species (ROS). N-acetyl cysteine (NAC) is a precursor of the synthesis of …

Effect fraction of Bletilla striata (Thunb.) Reichb. f. alleviates LPS-induced acute lung injury by inhibiting p47phox/NOX2 and promoting the Nrf2/HO-1 signaling …

F Jiang, C Hua, J Pan, S Peng, D Ning, C Chen, S Li… - Phytomedicine, 2024 - Elsevier
Abstract Background & Aims The effect fraction of Bletilla striata (Thunb.) Reichb. f.(EFBS), a
phenolic-rich extract, has significant protective effects on lipopolysaccharide (LPS)-induced …

Impact of N-Acetylcysteine in the mortality of patients hospitalized with COVID-19: a retrospective cohort study

MA Galindo-Andúgar, ÁA Arias, JAG Guerra… - Revista Clínica …, 2023 - Elsevier
Introduction and aim N-Acetylcysteine has been proposed for the treatment of COVID-19
thanks to its mucolytic, antioxidant and anti-inflammatory effects. Our aim is to evaluate its …

Molecular Mechanisms of N-Acetylcysteine in RSV Infections and Air Pollution-Induced Alterations: A Scoping Review

A Wrotek, A Badyda, T Jackowska - International Journal of Molecular …, 2024 - mdpi.com
N-acetylcysteine (NAC) is a mucolytic agent with antioxidant and anti-inflammatory
properties. The respiratory syncytial virus (RSV) is one of the most important etiological …

Wine-and stir-frying processing of Cuscutae Semen enhance its ability to alleviate oxidative stress and apoptosis via the Keap 1-Nrf2/HO-1 and PI3K/AKT pathways in …

Y Liang, Y Shi, R Guo, C Xu, M Fu, J Shen… - … Medicine and Therapies, 2024 - Springer
Abstract Background Cuscutae Semen (CS) has been prescribed in traditional Chinese
medicine (TCM) for millennia as an aging inhibitor, an anti-inflammatory agent, a pain …

Effect of N-Acetylcysteine on initial Carious Enamel Lesions in primary teeth: an In-vitro study

SM Mahfouz Omer, RH El-Sherbiny, SS El-Desouky - BMC Oral Health, 2023 - Springer
Background Dental caries initiates with non-cavitated enamel lesions as the first stage. The
cariogenic potential of N-Acetylcysteine (NAC) may be due to its usage frequency and form …

Clinical efficacy of N-acetylcysteine for COVID-19: A systematic review and meta-analysis of randomized controlled trials

TH Liu, JY Wu, PY Huang, YW Tsai, WH Hsu… - Heliyon, 2024 - cell.com
Background The association between N-acetylcysteine (NAC) and COVID-19 remains
undetermined; therefore, this meta-analysis assessed the clinical efficacy of NAC in the …

Efecto de la N-acetilcisteína en la mortalidad de pacientes ingresados por COVID-19: estudio de cohorte retrospectivo

MA Galindo-Andúgar, AA Arias, JAG Guerra… - Revista Clínica …, 2023 - Elsevier
Introducción y objetivo La N-acetilcisteína se ha propuesto para el tratamiento de COVID-19
gracias a sus efectos mucolítico, antioxidante y antiinflamatorio. El presente estudio tiene …