The etiology of preeclampsia

E Jung, R Romero, L Yeo, N Gomez-Lopez… - American journal of …, 2022 - Elsevier
Preeclampsia is one of the “great obstetrical syndromes” in which multiple and sometimes
overlapping pathologic processes activate a common pathway consisting of endothelial cell …

The oral microbiome: diversity, biogeography and human health

JL Baker, JL Mark Welch, KM Kauffman… - Nature Reviews …, 2024 - nature.com
The human oral microbiota is highly diverse and has a complex ecology, comprising
bacteria, microeukaryotes, archaea and viruses. These communities have elaborate and …

Interconnection of periodontal disease and comorbidities: Evidence, mechanisms, and implications

G Hajishengallis - Periodontology 2000, 2022 - Wiley Online Library
Periodontitis, a microbiome‐driven inflammatory disease of the tooth‐attachment apparatus,
is epidemiologically linked with other disorders, including cardio‐metabolic, cognitive …

[HTML][HTML] Periodontal disease: the good, the bad, and the unknown

LM Sedghi, M Bacino, YL Kapila - Frontiers in cellular and infection …, 2021 - frontiersin.org
Periodontal disease is classically characterized by progressive destruction of the soft and
hard tissues of the periodontal complex, mediated by an interplay between dysbiotic …

A guide to complement biology, pathology and therapeutic opportunity

DC Mastellos, G Hajishengallis… - Nature Reviews …, 2024 - nature.com
Complement has long been considered a key innate immune effector system that mediates
host defence and tissue homeostasis. Yet, growing evidence has illuminated a broader …

[HTML][HTML] Maladaptive innate immune training of myelopoiesis links inflammatory comorbidities

X Li, H Wang, X Yu, G Saha, L Kalafati, C Ioannidis… - Cell, 2022 - cell.com
Bone marrow (BM)-mediated trained innate immunity (TII) is a state of heightened immune
responsiveness of hematopoietic stem and progenitor cells (HSPC) and their myeloid …

2D MOF periodontitis photodynamic ion therapy

J Li, S Song, J Meng, L Tan, X Liu… - Journal of the …, 2021 - ACS Publications
Traditional surgical intervention and antibiotic treatment are poor and even invalid for
chronic diseases including periodontitis induced by diverse oral pathogens, which often …

Microenvironment-responsive metal-phenolic nanozyme release platform with antibacterial, ROS scavenging, and osteogenesis for periodontitis

Y Xu, Y Luo, Z Weng, H Xu, W Zhang, Q Li, H Liu… - ACS …, 2023 - ACS Publications
Periodontitis is a chronic inflammatory disease deriving from dental plaque, characterized by
the excessive accumulation of reactive oxygen species (ROS), matrix metalloproteinase …

Association between periodontal diseases and cardiovascular diseases, diabetes and respiratory diseases: Consensus report of the Joint Workshop by the European …

D Herrera, M Sanz, L Shapira, C Brotons… - Journal of clinical …, 2023 - Wiley Online Library
Aim To explore the implications for dentists and family doctors of the association between
periodontal and systemic diseases and the role of dentists and family doctors in managing …

Fusobacterium nucleatum, a key pathogenic factor and microbial biomarker for colorectal cancer

N Wang, JY Fang - Trends in Microbiology, 2023 - cell.com
Colorectal cancer (CRC), one of the most prevalent cancers, has complex etiology. The
dysbiosis of intestinal bacteria has been highlighted as an important contributor to CRC …