Adult skeletal muscle in mammals is a stable tissue under normal circumstances but has
remarkable ability to repair after injury. Skeletal muscle regeneration is a highly orchestrated …

In 1961, the satellite cell was first identified when electron microscopic examination of
skeletal muscle demonstrated a cell wedged between the plasma membrane of the muscle …

A central question in stem cell biology is the relationship between stem cells and their niche.
Although previous reports have uncovered how signaling molecules released by niche cells …

Muscle injury induces strong changes in muscle cells and extracellular matrix. Muscle
regeneration after injury has similarities to muscle development during embryogenesis and …

Muscular dystrophies such as Duchenne muscular dystrophy (DMD) are usually
approached as dysfunctions of the affected skeletal myofibres and their force transmission …

In skeletal muscle, growth of capillaries is an important adaptation to exercise training that
secures adequate diffusion capacity for oxygen and nutrients even at high‐intensity exercise …

Adult skeletal muscle generates force in a controlled and directed manner through the
contraction of highly specialized, postmitotic, multinucleated myofibers. Life-long muscle …

The muscle satellite cell is essential for skeletal muscle regeneration. It is located on the
muscle fibre, under the basal lamina as a quiescent cell, which becomes activated after …

Matrix metalloproteases (MMPs) are key regulatory molecules in the formation, remodeling,
and degradation of extracellular matrix (ECM) components in both physiological and …

Muscle stem cell (satellite cell) activation post muscle injury is a transient and critical step in
muscle regeneration. It is regulated by physiological cues, signaling molecules, and …