Thiols as a privileged scaffold against metallo-β-lactamases

C Chen, D Wang, KW Yang - Privileged Scaffolds in Drug Discovery, 2023 - Elsevier
Gram-negative bacteria producing metallo-β-lactamases (MβLs), which hydrolyze almost all
β-lactams, including penicillins, cephalosporins, and carbapenems, are important …

Fluorinated Captopril Analogues as Inhibitors of the Metallo-Β-Lactamase NDM-1

A Kondratieva, K Palica, C Frøhlich, HKS Leiros… - Available at SSRN … - papers.ssrn.com
Bacterial resistance to the majority of clinically used β-lactam antibiotics is a global health
threat and, consequently, the driving force for the development of new inhibitors. In this …