Quality of life and neuropsychiatric disorders in patients with Graves' Orbitopathy: Current concepts

A Bruscolini, M Sacchetti, M La Cava, M Nebbioso… - Autoimmunity …, 2018 - Elsevier
Graves' disease (GD) is an autoimmune chronic thyroiditis frequently associated with
development of Graves' orbitopathy (GO) characterized by proptosis, strabismus, impairment …

Computed tomography and magnetic resonance imaging approaches to Graves' ophthalmopathy: a narrative review

R Luccas, CM Riguetto, M Alves… - Frontiers in …, 2024 - frontiersin.org
Graves' ophthalmopathy (GO) affects up to 50% of patients with Graves' disease (GD)
ranging from mild ocular irritation to vision loss. The initial diagnosis is based on clinical …

Altered dynamic brain activity and functional connectivity in thyroid‐associated ophthalmopathy

WH Jiang, J Liu, J Zhou, Q Wu, XY Pu… - Human Brain …, 2023 - Wiley Online Library
Although previous neuroimaging evidence has confirmed the brain functional disturbances
in thyroid‐associated ophthalmopathy (TAO), the dynamic characteristics of brain activity …

Local-to-remote brain functional connectivity in patients with thyroid-associated ophthalmopathy and assessment of its predictive value using machine learning

Z Wen, X Wan, CX Qi, X Huang - International Journal of General …, 2022 - Taylor & Francis
Purpose To explore the alterations in both local and remote brain connectivity in patients
with thyroid-associated ophthalmopathy (TAO) and to investigate whether the alterations of …

Aberrant brain voxel‐wise resting state fMRI in patients with thyroid‐associated ophthalmopathy

W Chen, Q Wu, L Chen, J Zhou, HH Chen… - Journal of …, 2021 - Wiley Online Library
ABSTRACT Background and Purpose Although ophthalmic complaints were mostly
mentioned in thyroid‐associated ophthalmopathy (TAO), emotional and psychological …

Disrupted spontaneous neural activity in patients with thyroid-associated ophthalmopathy: a resting-state fMRI study using amplitude of low-frequency fluctuation

W Chen, Q Wu, L Chen, J Zhou, HH Chen… - Frontiers in Human …, 2021 - frontiersin.org
Purpose The purpose of the study was to investigate the brain functional alteration in
patients with thyroid-associated ophthalmopathy (TAO) by evaluating the spontaneous …

Altered static and dynamic interhemispheric resting-state functional connectivity in patients with thyroid-associated ophthalmopathy

W Chen, H Hu, Q Wu, L Chen, J Zhou… - Frontiers in …, 2021 - frontiersin.org
Purpose: Thyroid-associated ophthalmopathy (TAO) is a debilitating and sight-threatening
autoimmune disease that severely impairs patients' quality of life. Besides the most common …

Morphological and microstructural brain changes in thyroid-associated ophthalmopathy: a combined voxel-based morphometry and diffusion tensor imaging study

Q Wu, H Hu, W Chen, HH Chen, L Chen, XQ Xu… - Journal of …, 2020 - Springer
Purpose To explore the morphological and microstructural changes of grey and white matter
in the patients of thyroid-associated ophthalmopathy (TAO). Methods Twenty-five TAO …

Preliminary diffusion‐tensor imaging evidence for trans‐synaptic axonal degeneration in dysthyroid optic neuropathy due to thyroid‐associated ophthalmopathy

P Liu, B Luo, L Chen, QX Wang, LH Zhai… - Journal of Magnetic …, 2023 - Wiley Online Library
Background The mechanism driving dysthyroid optic neuropathy (DON) is unclear. Diffusion‐
tensor imaging (DTI) allows for noninvasively assessing the microstructure of the entire …

Depression-and anxiety-associated disrupted brain structural networks revealed by probabilistic tractography in thyroid associated ophthalmopathy

L Luo, L Gao, D Li, H Wen - Journal of Affective Disorders, 2024 - Elsevier
Background Patients with thyroid-associated opthalmopathy (TAO) have widespread white
matter (WM) abnormalities in the emotional and cognitive functional regions. However, the …