The intersecting pandemics of tuberculosis and COVID-19: population-level and patient-level impact, clinical presentation, and corrective interventions

K Dheda, T Perumal, H Moultrie, R Perumal… - The Lancet …, 2022 - thelancet.com
The global tuberculosis burden remains substantial, with more than 10 million people newly
ill per year. Nevertheless, tuberculosis incidence has slowly declined over the past decade …

Risk factors of severe COVID-19: a review of host, viral and environmental factors

L Zsichla, V Müller - Viruses, 2023 - mdpi.com
The clinical course and outcome of COVID-19 are highly variable, ranging from
asymptomatic infections to severe disease and death. Understanding the risk factors of …

Tuberculosis and COVID-19 co-infection: description of the global cohort

TB/COVID-19 Global Study Group - European Respiratory …, 2022 - Eur Respiratory Soc
Background Information on tuberculosis (TB) and coronavirus disease 2019 (COVID-19) is
still limited. The aim of this study was to describe the features of the TB/COVID-19 co …

Escape from recognition of SARS-CoV-2 variant spike epitopes but overall preservation of T cell immunity

C Riou, R Keeton, T Moyo-Gwete… - Science translational …, 2021 - science.org
SARS-CoV-2 variants that escape neutralization and potentially affect vaccine efficacy have
emerged. T cell responses play a role in protection from reinfection and severe disease, but …

Prior infection with SARS-CoV-2 boosts and broadens Ad26. COV2. S immunogenicity in a variant-dependent manner

R Keeton, SI Richardson, T Moyo-Gwete, T Hermanus… - Cell host & …, 2021 - cell.com
Summary The Johnson and Johnson Ad26. COV2. S single-dose vaccine represents an
attractive option for coronavirus disease 2019 (COVID-19) vaccination in countries with …

[HTML][HTML] The definition of tuberculosis infection based on the spectrum of tuberculosis disease

GB Migliori, CWM Ong, L Petrone, L D'Ambrosio… - Breathe, 2021 - Eur Respiratory Soc
Latent tuberculosis infection was the term traditionally used to indicate tuberculosis (TB)
infection. This term was used to define “a state of persistent immune response to stimulation …

The immune response to SARS-CoV-2 in people with HIV

MA Höft, WA Burgers, C Riou - Cellular & Molecular Immunology, 2024 - nature.com
This review examines the intersection of the HIV and SARS-CoV-2 pandemics. People with
HIV (PWH) are a heterogeneous group that differ in their degree of immune suppression …

Impact of aging on immunity in the context of COVID-19, HIV, and tuberculosis

A Grifoni, T Alonzi, G Alter, DMC Noonan… - Frontiers in …, 2023 - frontiersin.org
Knowledge of aging biology needs to be expanded due to the continuously growing number
of elderly people worldwide. Aging induces changes that affect all systems of the body. The …

Effects of tuberculosis and/or HIV-1 infection on COVID-19 presentation and immune response in Africa

E Du Bruyn, C Stek, R Daroowala… - Nature …, 2023 - nature.com
Few studies from Africa have described the clinical impact of co-infections on SARS-CoV-2
infection. Here, we investigate the presentation and outcome of SARS-CoV-2 infection in an …

[HTML][HTML] T cell immunity to SARS-CoV-2

J Niessl, T Sekine, M Buggert - Seminars in immunology, 2021 - Elsevier
Exceptional efforts have been undertaken to shed light into the biology of adaptive immune
responses to SARS-CoV-2. T cells occupy a central role in adaptive immunity to mediate …