BY Choi, M Han, JW Kwak, TH Kim - Genes, 2021 - mdpi.com
The pathogenesis of allergic rhinitis is associated with genetic, environmental, and epigenetic factors. Genotyping of single nucleotide polymorphisms (SNPs) is an advanced …
JS Hawe, R Wilson, KT Schmid, L Zhou… - Nature …, 2022 - nature.com
We determined the relationships between DNA sequence variation and DNA methylation using blood samples from 3,799 Europeans and 3,195 South Asians. We identify …
Global epidemiological studies show that chronic non-communicable diseases such as atherosclerosis and metabolic disorders represent the leading cause of premature mortality …
A Domingo-Relloso, K Makhani… - Circulation …, 2022 - Am Heart Assoc
Background: Epigenetic dysregulation has been proposed as a key mechanism for arsenic- related cardiovascular disease (CVD). We evaluated differentially methylated positions …
B Zhang, H Jiang, Z Dong, A Sun, J Ge - Genes & diseases, 2021 - Elsevier
Abstract N6-methyladenosine (m6A) RNA methylation is an emerging area of epigenetics, which is a reversible and dynamic modification mediating by 'writers'(methylase, adding …
H Cao, L Li, D Yang, L Zeng, X Yewei, B Yu… - European Journal of …, 2019 - Elsevier
Epigenetics is the study of heritable changes in gene expression without changing the DNA sequence-a change in phenotype without a change in genotype. Epigenetic abnormalities …
Epigenetic changes are required for normal development, yet the nature and respective contribution of factors that drive epigenetic variation in humans remain to be fully …
PA Dugué, CH Jung, JE Joo, X Wang, EM Wong… - Epigenetics, 2020 - Taylor & Francis
We conducted a genome-wide association study of blood DNA methylation and smoking, attempted replication of previously discovered associations, and assessed the reversibility of …
Importance American Indian communities experience a high burden of coronary heart disease (CHD). Strategies are needed to identify individuals at risk and implement …