Oxidative stress plays an essential role in the pathogenesis of chronic diseases such as
cardiovascular diseases, diabetes, neurodegenerative diseases, and cancer. Long term …

Numerous plant compounds and their metal-ion complexes exert antioxidative, anti-
inflammatory, anticancer, and other beneficial effects. This review highlights the different …

The management of patients with autoimmune rheumatic diseases such as rheumatoid
arthritis (RA) remains a significant challenge. Often the rheumatologist is restricted to …

Reactive oxygen species (ROS) and their products are components of cell signaling
pathways and play important roles in cellular physiology and pathophysiology. Under …

Redox biology is at the core of life sciences, accompanied by the close correlation of redox
processes with biological activities. Redox homeostasis is a prerequisite for human health …

Abstract Hydrogen peroxide (H2O2) acts as a signaling messenger by triggering the
reversible oxidation of redox-regulated proteins. It remains unclear how proteins can be …

Peroxiredoxins (PRDXs) are a ubiquitously expressed family of small (22‑27 kDa) non‑
seleno peroxidases that catalyze the peroxide reduction of H2O2, organic hydroperoxides …

Oxidative stress is one of the hallmarks of cancer. Tumorigenesis and progression are
accompanied by elevated reactive oxygen species (ROS) levels and adaptive elevation of …

Reduction and oxidation reactions are essential for biochemical processes. They are part of
metabolic pathways and signal transduction. Reactive oxygen species (ROS) as second …

Life on Earth evolved in the presence of hydrogen peroxide, and other peroxides also
emerged before and with the rise of aerobic metabolism. They were considered only as toxic …