Y Du, N Kong, J Zhang - Frontiers in genetics, 2021 - frontiersin.org
Age-related macular degeneration (AMD) is the most common cause of irreversible vision loss in the developed world which affects the quality of life for millions of elderly individuals …
Age‐related macular degeneration (AMD) is a devastating eye disease that causes permanent vision loss in the central part of the retina, known as the macula. Patients with …
L Wang, W Wei, YJ Zhao, S Chen, D Wu… - Experimental Eye …, 2024 - Elsevier
This study aims to determine the risk associated with early age-related macular degeneration (AMD) due to refractive errors (RE) using an analysis of genome-wide …
R Terao, BS Sohn, T Yamamoto, TJ Lee… - … & Visual Science, 2024 - jov.arvojournals.org
Purpose: Dysregulated cholesterol metabolism is critical in the pathogenesis of AMD. Cellular senescence contributes to the development of numerous age-associated diseases …
RH Guymer, R Silva, M Ghadessi, S Leal… - … & Visual Science, 2024 - tvst.arvojournals.org
Purpose: This analysis investigated potential associations between gene variants and clinical end points in the VIEW 1 and 2 randomized clinical trials of intravitreal aflibercept …
M Zhang, L Duan, Y Feng - Medicine, 2024 - journals.lww.com
This study's goal is to evaluate if there is a causal connection between rheumatoid arthritis (RA) and age-related macular degeneration (AMD), despite past epidemiological studies …
MJ Simcoe, G Arno, PG Hysi, T Ko… - … & Visual Science, 2023 - iovs.arvojournals.org
Purpose: To determine whether the ABCA4 retinopathy-associated variant p. Asn1868Ile (c. 5603A> T) is associated with retinal structure or subclinical disease among the general …
D Garzone, MA Imtiaz, MM Mauschitz, NA Aziz… - Current eye …, 2024 - Taylor & Francis
Purpose Specific genetic factors might serve as markers for risk stratification of AMD progression, but their association with key features of AMD has not been fully elucidated …
Purpose: To explore genetic determinants specific to reticular pseudodrusen (RPD), and to compare these with genetic associations for drusen. Setting: Participants with RPD, drusen …