The aging of the population in the United States and throughout the developed world has
increased morbidity and mortality attributable to lung disease, while the morbidity and …

Chronic respiratory diseases (CRDs) are an important factor of morbidity and mortality,
accounting for approximately 6% of total deaths worldwide. The main CRDs are asthma and …

Extracellular vesicles (EVs) play a vital role in normal lung physiology to maintain
homeostasis in the airways via intercellular communication. EVs include exosomes and …

Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death
worldwide, with increasing prevalence, in particular in the elderly. COPD is characterised by …

Abstract Toll-like receptor 7 (TLR7) is known for eliciting immunity against single-stranded
RNA viruses, and is increased in both human and cigarette smoke (CS)-induced …

Chronic respiratory diseases encompass a group of diverse conditions affecting the airways,
which all impair lung function over time. They include cystic fibrosis (CF), idiopathic …

Chronic lung disease has become a leading cause of death in recent years. Despite several
attempts to discover and develop new therapeutic approaches, patients often suffer a poor …

Epigenetic responses due to environmental changes alter chromatin structure, which in turn
modifies the phenotype, gene expression profile, and activity of each cell type that has a role …

A large part of the human genome is transcribed in non-coding RNAs, transcripts that do not
code for protein, including microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) …

Chronic obstructive pulmonary disease (COPD) is a progressive lung disease and is
currently the fourth leading cause of death worldwide. Chronic inflammation and repair …