Molecular atlas of the adult mouse brain
Brain maps are essential for integrating information and interpreting the structure-function
relationship of circuits and behavior. We aimed to generate a systematic classification of the …
relationship of circuits and behavior. We aimed to generate a systematic classification of the …
The promise of spatial transcriptomics for neuroscience in the era of molecular cell typing
The stereotyped spatial architecture of the brain is both beautiful and fundamentally related
to its function, extending from gross morphology to individual neuron types, where soma …
to its function, extending from gross morphology to individual neuron types, where soma …
OpenML: networked science in machine learning
Many sciences have made significant breakthroughs by adopting online tools that help
organize, structure and mine information that is too detailed to be printed in journals. In this …
organize, structure and mine information that is too detailed to be printed in journals. In this …
Anterior hippocampus: the anatomy of perception, imagination and episodic memory
P Zeidman, EA Maguire - Nature Reviews Neuroscience, 2016 - nature.com
The brain creates a model of the world around us. We can use this representation to
perceive and comprehend what we see at any given moment, but also to vividly re …
perceive and comprehend what we see at any given moment, but also to vividly re …
Bridging the gap between connectome and transcriptome
The recent construction of brain-wide gene expression atlases, which measure the
transcriptional activity of thousands of genes in multiple anatomical locations, has made it …
transcriptional activity of thousands of genes in multiple anatomical locations, has made it …
A community-based transcriptomics classification and nomenclature of neocortical cell types
To understand the function of cortical circuits, it is necessary to catalog their cellular
diversity. Past attempts to do so using anatomical, physiological or molecular features of …
diversity. Past attempts to do so using anatomical, physiological or molecular features of …
Parkinson-associated risk variant in distal enhancer of α-synuclein modulates target gene expression
F Soldner, Y Stelzer, CS Shivalila, BJ Abraham… - Nature, 2016 - nature.com
Genome-wide association studies (GWAS) have identified numerous genetic variants
associated with complex diseases, but mechanistic insights are impeded by a lack of …
associated with complex diseases, but mechanistic insights are impeded by a lack of …
Adolescence is associated with genomically patterned consolidation of the hubs of the human brain connectome
KJ Whitaker, PE Vértes… - Proceedings of the …, 2016 - National Acad Sciences
How does human brain structure mature during adolescence? We used MRI to measure
cortical thickness and intracortical myelination in 297 population volunteers aged 14–24 y …
cortical thickness and intracortical myelination in 297 population volunteers aged 14–24 y …
Reference-free cell type deconvolution of multi-cellular pixel-resolution spatially resolved transcriptomics data
Recent technological advancements have enabled spatially resolved transcriptomic profiling
but at multi-cellular pixel resolution, thereby hindering the identification of cell-type-specific …
but at multi-cellular pixel resolution, thereby hindering the identification of cell-type-specific …
[HTML][HTML] Master transcription factors and mediator establish super-enhancers at key cell identity genes
Summary Master transcription factors Oct4, Sox2, and Nanog bind enhancer elements and
recruit Mediator to activate much of the gene expression program of pluripotent embryonic …
recruit Mediator to activate much of the gene expression program of pluripotent embryonic …