Gene expression elucidates functional impact of polygenic risk for schizophrenia
Over 100 genetic loci harbor schizophrenia-associated variants, yet how these variants
confer liability is uncertain. The CommonMind Consortium sequenced RNA from …
confer liability is uncertain. The CommonMind Consortium sequenced RNA from …
Multiscale and integrative single-cell Hi-C analysis with Higashi
Abstract Single-cell Hi-C (scHi-C) can identify cell-to-cell variability of three-dimensional
(3D) chromatin organization, but the sparseness of measured interactions poses an analysis …
(3D) chromatin organization, but the sparseness of measured interactions poses an analysis …
Morphometric similarity networks detect microscale cortical organization and predict inter-individual cognitive variation
Macroscopic cortical networks are important for cognitive function, but it remains challenging
to construct anatomically plausible individual structural connectomes from human …
to construct anatomically plausible individual structural connectomes from human …
Consciousness: here, there and everywhere?
The science of consciousness has made great strides by focusing on the behavioural and
neuronal correlates of experience. However, while such correlates are important for …
neuronal correlates of experience. However, while such correlates are important for …
The modular and integrative functional architecture of the human brain
MA Bertolero, BTT Yeo… - Proceedings of the …, 2015 - National Acad Sciences
Network-based analyses of brain imaging data consistently reveal distinct modules and
connector nodes with diverse global connectivity across the modules. How discrete the …
connector nodes with diverse global connectivity across the modules. How discrete the …
Transcriptional landscape of the prenatal human brain
The anatomical and functional architecture of the human brain is mainly determined by
prenatal transcriptional processes. We describe an anatomically comprehensive atlas of the …
prenatal transcriptional processes. We describe an anatomically comprehensive atlas of the …
Norepinephrine ignites local hotspots of neuronal excitation: How arousal amplifies selectivity in perception and memory
Emotional arousal enhances perception and memory of high-priority information but impairs
processing of other information. Here, we propose that, under arousal, local glutamate levels …
processing of other information. Here, we propose that, under arousal, local glutamate levels …
A high-resolution in vivo atlas of the human brain's serotonin system
The serotonin (5-hydroxytryptamine, 5-HT) system modulates many important brain
functions and is critically involved in many neuropsychiatric disorders. Here, we present a …
functions and is critically involved in many neuropsychiatric disorders. Here, we present a …
Hybridization-based in situ sequencing (HybISS) for spatially resolved transcriptomics in human and mouse brain tissue
D Gyllborg, CM Langseth, X Qian, E Choi… - Nucleic acids …, 2020 - academic.oup.com
Visualization of the transcriptome in situ has proven to be a valuable tool in exploring single-
cell RNA-sequencing data, providing an additional spatial dimension to investigate …
cell RNA-sequencing data, providing an additional spatial dimension to investigate …
[HTML][HTML] A meta-analysis of sex differences in human brain structure
The prevalence, age of onset, and symptomatology of many neuropsychiatric conditions
differ between males and females. To understand the causes and consequences of sex …
differ between males and females. To understand the causes and consequences of sex …