Interleukin-18 (IL-18) is a potent pro-inflammatory cytokine involved in host defense against
infections and regulates the innate and acquired immune response. IL-18 is produced by …

Review: Interleukin-18 (IL-18) is a proinflammatory cytokine that promotes various innate
immune processes related to infection, inflammation, and autoimmunity. Patients with …

Multisystem inflammatory syndrome in children is a post-infectious presentation SARS-CoV-
2 associated with expansion of the T cell receptor Vβ21. 3+ T-cell subgroup. Here we apply …

Systemic juvenile idiopathic arthritis (sJIA) is a serious multifactorial autoinflammatory
disease with a significant mortality rate due to macrophage activation syndrome (MAS) …

Background Systemic inflammation is a significant mechanism underpinning adverse
cognitive changes. Sleep quality is a crucial factor associated with systemic inflammation …

Background Autoinflammation with infantile enterocolitis (AIFEC) is an often fatal disease
caused by gain-of-function mutations in the NLRC4 inflammasome. This …

Hemophagocytic lymphohistiocytosis (HLH)–like toxicities are increasingly being
recognized as complications of chimeric antigen receptor (CAR) T-cell therapy. Clinical …

The immune response to the SARS-CoV-2 infection is crucial to the patient outcome. IL-18 is
involved in the lymphocyte response to the disease and it is well established its important …

NLRP3 is a molecular sensor recognizing a wide range of danger signals. Its activation
leads to the assembly of an inflammasome that allows for activation of caspase-1 and …

The liver has the unique capacity to regenerate, and up to 70% of the liver can be removed
without detrimental consequences to the organism. Liver regeneration is a complex process …