Roseburia intestinalis (R. intestinalis) is an anaerobic, Gram-positive, slightly curved rod-
shaped flagellated bacterium that produces butyrate in the colon. R. intestinalis has been …

The gut microbiota has been linked to the emergence of obesity, metabolic syndrome and
the onset of type 2 diabetes through decreased glucose tolerance and insulin resistance …

In the last two decades, considerable interest has been shown in understanding the
development of the gut microbiota and its internal and external effects on the intestine, as …

Crosstalk between the gut microbiota and the host has attracted considerable attention
owing to its involvement in diverse diseases. Chronic kidney disease (CKD) is commonly …

Objective Patients with renal failure suffer from symptoms caused by uraemic toxins,
possibly of gut microbial origin, as deduced from studies in animals. The aim of the study is …

Despite major strides in reducing cardiovascular disease (CVD) burden with modification of
classic CVD risk factors, significant residual risks remain. Recent discoveries that linked …

Diabetic kidney disease (DKD) is a progressive disorder, which is increasing globally in
prevalence due to the increased incidence of obesity and diabetes mellitus. Despite optimal …

Dysbiosis represents changes in composition and structure of the gut microbiome
community (microbiome), which may dictate the physiological phenotype (health or …

Diabetic kidney disease is a major cause of renal failure that urgently necessitates a
breakthrough in disease management. Here we show using untargeted metabolomics that …

Choline is a water-soluble nutrient essential for human life. Gut microbial metabolism of
choline results in the production of trimethylamine (TMA), which, upon absorption by the host …