ABSTRACT SARS-CoV-2 tropism for the ACE2 receptor, along with the multifaceted
inflammatory reaction, is likely to drive the generalized hypercoagulable and thrombotic …

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led
to an unprecedented global healthcare crisis. While SARS-CoV-2-associated COVID-19 …

Background Endotheliopathy and coagulopathy appear to be the main causes for critical
illness and death in patients with coronavirus disease 2019 (COVID-19). The adhesive …

Venous thromboembolism is a very common and costly health problem. Deep-vein
thrombosis (DVT) can cause permanent damage to the venous system and lead to swelling …

Clinical viscoelastic hemostatic assays, which have been used for decades, rely on
measuring biomechanical responses to physical stimuli but face challenges related to high …

Background Atherosclerosis is the salient, underlying cause of cardiovascular diseases,
such as arrhythmia, coronary artery disease, cardiomyopathy, pulmonary embolism and …

Background Hyperinflammation and coagulopathy are hallmarks of COVID-19 and
synergistically contribute to illness progression. Antiplatelet agents have been proposed as …

As COVID-19 continues, an increasing number of patients develop long COVID symptoms
varying in severity that last for weeks, months, or longer. Symptoms commonly include …

The complications of pulmonary thrombosis caused by the coronavirus pneumonia have
created an unprecedented clinical need for efficient targeted therapy of pulmonary …

COVID-19, caused by the SARS-CoV-2 virus, has revealed a complex interplay between
inflammation and coagulation, leading to the emergence of the concept of thrombo …