Hepatic grafts from non-heartbeating donors may alleviate the organ shortage, but they
inherently suffer from warm ischemia. In the present study, we tested our hypothesis that …

The increasing incidence of congestive heart failure has stimulated efforts to develop
pharmacologic strategies to prevent or reverse the associated process of adverse cardiac …

The enzyme adenosine kinase constitutes the major purine nucleoside phosphorylating
activity in mammalian cells. In view of its central role in adenosine metabolism, which is an …

In the late 19th century, Sir William Osler noted that patients with myocardial damage due to
valvular heart disease had a highly variable clinical course. Some patients remained free of …

Adenosine is a product of adenylate phosphate breakdown that can exert protective effects
on tissues during energy limitation. Accumulation of cardiac adenosine under hypoxia is …

Introduction: High pulmonary artery flow rates can result in severe reperfusion injury after
lung transplantation. Our hypothesis was that selective activation of the adenosine A 2A …

Background No previous studies have examined actions of adenosine or related
compounds after blunt chest trauma, but we have shown that the prototype adenosine …

It has been suggested that calcitonin gene‐related peptide (CGRP) is involved in the
protection provided by ischaemic preconditioning in rat hearts and that ischaemic …

The enzyme adenosine kinase (AK; EC 2.7. 1.20) shows a dependence upon inorganic
phosphate (Pi) for activity. The degree of dependence varies among enzyme sources and …

Adenosine is an ubiquitously occurring endogenous nucleoside that via cell surface
receptors exerts multiple antihypertensive actions, and mediates a number of biological …