Omicron genetic and clinical peculiarities that may overturn SARS-CoV-2 pandemic: a literature review

G Tiecco, S Storti, M Degli Antoni, E Focà… - International Journal of …, 2022 - mdpi.com
The Coronavirus disease 2019 (COVID-19) pandemic poses a great threat to global public
health. The original wild-type strain of severe acute respiratory syndrome coronavirus 2 …

Omicron BA. 2 lineage, the “stealth” variant: is it truly a silent epidemic? A literature review

G Tiecco, S Storti, S Arsuffi, M Degli Antoni… - International Journal of …, 2022 - mdpi.com
The epidemic curve of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
silently rising again. Worldwide, the dominant SARS-CoV-2 variant of concern (VOC) is …

[PDF][PDF] TMEM106B is a receptor mediating ACE2-independent SARS-CoV-2 cell entry

J Baggen, M Jacquemyn, L Persoons, E Vanstreels… - Cell, 2023 - cell.com
SARS-CoV-2 is associated with broad tissue tropism, a characteristic often determined by
the availability of entry receptors on host cells. Here, we show that TMEM106B, a lysosomal …

SARS-CoV-2: recent variants and clinical efficacy of antibody-based therapy

DD Singh, A Sharma, HJ Lee… - Frontiers in cellular and …, 2022 - frontiersin.org
Multiple variants of SARS-CoV-2 have emerged and are now prevalent at the global level.
Currently designated variants of concern (VOCs) are B. 1.1. 7, B1. 351, P. 1, B. 1.617. 2 …

Traditional Chinese medicines against COVID-19: a global overview

CL Yao, WL Wei, JQ Zhang, QR Bi, JY Li… - World Journal of …, 2022 - journals.lww.com
Abstract Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory
syndrome coronavirus 2, continues to be a global concern. Traditional Chinese medicines …

Bioinformatics and immunoinformatics approach to develop potent multi-peptide vaccine for coxsackievirus B3 capable of eliciting cellular and humoral immune …

A Ullah, M Waqas, S Aziz, S ur Rahman, S Khan… - International Journal of …, 2023 - Elsevier
Abstract Coxsackievirus B3 (CVB3) is a viral pathogen of various human disorders with no
effective preventative interventions. Herein, we aimed to design a chimeric vaccine construct …

Designing a multi-epitope vaccine against coxsackievirus B based on immunoinformatics approaches

S Huang, C Zhang, J Li, Z Dai, J Huang… - Frontiers in …, 2022 - frontiersin.org
Coxsackievirus B (CVB) is one of the major viral pathogens of human myocarditis and
cardiomyopathy without any effective preventive measures; therefore, it is necessary to …

“Flash & Click”: Multifunctionalized Lipid Derivatives as Tools To Study Viral Infections

C Schultz, SE Farley, FG Tafesse - Journal of the American …, 2022 - ACS Publications
In this perspective article, we describe the current status of lipid tools for studying host lipid–
virus interactions at the cellular level. We discuss the potential lipidomic changes that viral …

Most frequently harboured missense variants of hACE2 across different populations exhibit varying patterns of binding interaction with spike glycoproteins of emerging …

A Tahsin, R Ahmed, P Bhattacharjee, M Adiba… - Computers in Biology …, 2022 - Elsevier
Since the emergence of SARS-CoV-2 at Wuhan in the Hubei province of China in 2019, the
virus has accumulated various mutations, giving rise to many variants. According to the …

A clinical update on SARS-CoV-2: Pathology and development of potential inhibitors

DD Singh, I Han, EH Choi, DK Yadav - Current Issues in Molecular …, 2023 - mdpi.com
SARS-CoV-2 (severe acute respiratory syndrome) is highly infectious and causes severe
acute respiratory distress syndrome (SARD), immune suppression, and multi-organ failure …