[HTML][HTML] Hepatocellular carcinoma in non-alcoholic fatty liver disease: an emerging menace

G Baffy, EM Brunt, SH Caldwell - Journal of hepatology, 2012 - Elsevier
Hepatocellular carcinoma (HCC) is a common cancer worldwide that primarily develops in
cirrhosis resulting from chronic infection by hepatitis B virus and hepatitis C virus, alcoholic …

Obesity-associated mechanisms of hepatocarcinogenesis

R Karagozian, Z Derdák, G Baffy - Metabolism, 2014 - Elsevier
Obesity has been recognized as a key component of the metabolic syndrome, a cluster of
risk factors associated with diabetes and cardiovascular morbidity. In addition, obesity has …

[HTML][HTML] Identification of liver cancer progenitors whose malignant progression depends on autocrine IL-6 signaling

G He, D Dhar, H Nakagawa, J Font-Burgada, H Ogata… - Cell, 2013 - cell.com
Hepatocellular carcinoma (HCC) is a slowly developing malignancy postulated to evolve
from premalignant lesions in chronically damaged livers. However, it was never established …

[PDF][PDF] Hepatocyte IKKβ/NF-κB inhibits tumor promotion and progression by preventing oxidative stress-driven STAT3 activation

G He, GY Yu, V Temkin, H Ogata, C Kuntzen, T Sakurai… - Cancer cell, 2010 - cell.com
The NF-κB activating kinase IKKβ suppresses early chemically induced liver tumorigenesis
by inhibiting hepatocyte death and compensatory proliferation. To study IKKβ's role in late …

[PDF][PDF] Pathologic diagnosis of early hepatocellular carcinoma: a report of the international consensus group for hepatocellular neoplasia

International Consensus Group for Hepatocellular … - …, 2009 - Wiley Online Library
Materials and Methods Twenty-six resected cases of nodules from 23 patients with chronic
hepatitis or cirrhosis caused by hepatitis B or Abbreviations: GPC3, glypican-3; GS …

Added value of gadoxetic acid–enhanced hepatobiliary phase MR imaging in the diagnosis of hepatocellular carcinoma

SS Ahn, MJ Kim, JS Lim, HS Hong, YE Chung, JY Choi - Radiology, 2010 - pubs.rsna.org
Purpose To determine the added value of hepatobiliary phase images in gadoxetic acid–
enhanced magnetic resonance (MR) imaging in the evaluation of hepatocellular carcinoma …

The application of markers (HSP70 GPC3 and GS) in liver biopsies is useful for detection of hepatocellular carcinoma

L Di Tommaso, A Destro, JY Seok, E Balladore… - Journal of …, 2009 - Elsevier
BACKGROUND/AIMS: Liver biopsy for hepatocellular carcinoma (HCC) detection is largely
restricted to small hepatocellular lesions, which are often morphologically challenging …

The epidemiology of hepatocellular cancer: from the perspectives of public health problem to tumor biology

S Caldwell, SH Park - Journal of gastroenterology, 2009 - Springer
The epidemiology of hepatocellular cancer (HCC) can be viewed from several important
perspectives. The conventional perspective includes the overall public health impact of …

Multistep human hepatocarcinogenesis: correlation of imaging with pathology

M Kudo - Journal of gastroenterology, 2009 - Springer
Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide. The
majority of HCCs develop in cirrhotic livers, and the early detection and characterization of …

Update on precursor and early lesions of hepatocellular carcinomas

YN Park - Archives of pathology & laboratory medicine, 2011 - meridian.allenpress.com
Context.—There is increasing evidence to support a multistep model of the process of
human hepatocarcinogenesis. Precursor lesions are characterized by the appearance of …