Many drugs, or their antecedents, were discovered through observation of their effects on
normal or disease physiology. For the past generation, this phenotypic drug discovery …

Numerous drug treatments that have recently entered the clinic or clinical trials have their
genesis in zebrafish. Zebrafish are well established for their contribution to developmental …

The fast growth of industrialization combined with the increasing population has led to an
unparalleled demand for providing water in a safe, reliable, and cost-effective way, which …

To discover new molecules or review the biological activity and toxicity of therapeutic
substances, drug development, and research relies on robust biological systems to obtain …

The zebrafish (Danio rerio) is used as an embryonic and larval model to perform in vitro
experiments and developmental toxicity studies. Zebrafish may be used to determine the …

Mammalian models including non‐human primates, pigs and rodents have been used
extensively to study the mechanisms of cardiovascular disease. However, there is an …

Chemical imaging, especially mid-infrared spectroscopic microscopy, enables label-free
biomedical analyses while achieving expansive molecular sensitivity. However, its slow …

Nanoparticles (NP) are attractive options for the therapeutic delivery of active
pharmaceutical drugs, proteins and nucleic acids into cells, tissues and organs. Research …

The occurrence of neuroactive chemicals in the aquatic environment is on the rise and
poses a potential threat to aquatic biota of currently unpredictable outcome. In particular …

The current study paves the way for improved chemotherapy by creating pH-responsive
nanogels (NGs)(GC1 and GC2) loaded with synthetic ruthenium (II) arene complexes to …