Skeletal muscle fibrosis: an overview

MAA Mahdy - Cell and tissue research, 2019 - Springer
Extracellular matrix (ECM) is an essential component of skeletal muscle. It provides a
framework structure that holds myofibers and blood capillaries and nerves supplying the …

Hypoxia-stimulated cardiac fibroblast production of IL-6 promotes myocardial fibrosis via the TGF-β1 signaling pathway

JH Wang, L Zhao, X Pan, NN Chen, J Chen… - Laboratory …, 2016 - nature.com
Abstract Interlukin-6 (IL-6) is a multifunctional cytokine produced by several cell types that
has a role in fibrosis. Fibroblasts (FBs) maintain this underlying pathogenic change through …

Reactive oxygen species in skeletal muscle injury, fatigue, regeneration and ageing: In memory of John Faulkner The role of zinc and matrix metalloproteinases in …

F Ribeiro, X Zhang, Y Wen, N Cacciani… - Free Radical Biology …, 2024 - Elsevier
Due to an unexpected activation of different zinc (Zn) transporters in a recent prospective
clinical study, we have revisited the role of Zn homeostasis and the activation of matrix …

Regulation of extracellular matrix elements and sarcomerogenesis in response to different periods of passive stretching in the soleus muscle of rats

SM Peviani, V Guzzoni, CM Pinheiro-Dardis, YP Silva… - Scientific reports, 2018 - nature.com
Stretching is a common method used to prevent muscle shortening and improve limited
mobility. However, the effect of different time periods on stretching-induced adaptation of the …

[HTML][HTML] Effects of two intensities of treadmill exercise on neuromuscular recovery after median nerve crush injury in Wistar rats

MC Ferreira, MX Oliveira, JI Souza… - Journal of Exercise …, 2019 - ncbi.nlm.nih.gov
Considering the potential action of exercise on neuroplasticity and the need to adapt
protocols to enhance functional recovery after nerve injury, this study evaluated the effects of …

Efficacy of passive repetitive stretching of skeletal muscle on myofiber hypertrophy and genetic suppression on MAFbx, MuRF1, and myostatin

Y Wang, S Ikeda, K Ikoma - Journal of Muscle Research and Cell Motility, 2021 - Springer
Skeletal muscles undergo adaptations in response to mechanical stimuli such as stretching.
However, there is limited evidence regarding the hypertrophic effects of passive repetitive …

Passive properties of the wrist and fingers following chronic hemiparetic stroke: interlimb comparisons in persons with and without a clinical treatment history that …

BI Binder-Markey, WM Murray, JPA Dewald - Frontiers in neurology, 2021 - frontiersin.org
Background: Neural impairments that follow hemiparetic stroke may negatively affect
passive muscle properties, further limiting recovery. However, factors such as hypertonia …

Electrical stimulation based on chronaxie increases fibrosis and modulates TWEAK/Fn14, TGF-β/myostatin, and MMP pathways in denervated muscles

CM Pinheiro-Dardis, TL Russo - American Journal of Physical …, 2017 - journals.lww.com
Objective The aim of this work was to investigate the effects of electrical stimulation (ES) of
denervated muscles of rat in neuromuscular performance, muscle atrophy, and fibrosis …

[HTML][HTML] Negative neuromuscular and functional repercussion of forced swimming after axonotmesis

JA de Moura, J de Morais, SMN Barbosa… - Journal of Exercise …, 2022 - ncbi.nlm.nih.gov
Peripheral nerve injuries are cause of sensory disturbances and in functional abilities, and
are associated personal and social costs. Strategies that maximize nerve regeneration and …

[HTML][HTML] Morphometric and molecular muscle remodeling after passive stretching in elderly female rats

HRF Martins, TGG Zotz, SP Messa, LGA Capriglione… - Clinics, 2020 - SciELO Brasil
OBJECTIVES: To determine the effects of three sessions of a passive stretching exercise
protocol on the muscles of elderly female rats. METHODS: The effects of the stretching …