Genetic and Epigenetic Landscape for Drug Development in Polycystic Ovary Syndrome
Y Chen, G Wang, J Chen, C Wang, X Dong… - Endocrine …, 2024 - academic.oup.com
The treatment of polycystic ovary syndrome (PCOS) faces challenges as all known
treatments are merely symptomatic. The US Food and Drug Administration (FDA) has not …
treatments are merely symptomatic. The US Food and Drug Administration (FDA) has not …
[HTML][HTML] Whispers of the Polycystic Ovary Syndrome Theater: Directing Role of Long Noncoding RNAs
X Lin, X Nie, P Deng, L Wang, C Hu, N Jin - Non-coding RNA Research, 2024 - Elsevier
Abstract Polycystic Ovary Syndrome (PCOS) is a multifaceted endocrine disorder that
implicates a spectrum of clinical manifestations, including hormonal imbalance, metabolic …
implicates a spectrum of clinical manifestations, including hormonal imbalance, metabolic …
[HTML][HTML] Role of the NLRP3 inflammasome in gynecological disease
X Zheng, D Zhao, Y Jin, Y Liu, D Liu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
The NLR family pyrin domain containing 3 (NLRP3) inflammasome is involved in the innate
immune system and is a three-part macromolecular complex comprising the NLRP3 protein …
immune system and is a three-part macromolecular complex comprising the NLRP3 protein …
Down‐regulation of Lon protease 1 lysine crotonylation aggravates mitochondrial dysfunction in polycystic ovary syndrome
Y Xie, S Chen, Z Guo, Y Tian, X Hong, P Feng… - MedComm, 2023 - Wiley Online Library
Polycystic ovary syndrome (PCOS) is a prevalent reproductive endocrine disorder, with
metabolic abnormalities and ovulation disorders. The post‐translational modifications …
metabolic abnormalities and ovulation disorders. The post‐translational modifications …
Circ_0036490 and DKK1 competitively bind miR-29a to promote lipopolysaccharides-induced human gingival fibroblasts injury
Y Wu, B Li, D Deng, H Zhou, M Liu, H Ai, Y Xin… - …, 2024 - Taylor & Francis
MicroRNA (miRNA) plays a regulatory role in periodontitis. This study aimed to explore
whether miR-29a could affect lipopolysaccharides (LPSs)-induced injury in human gingival …
whether miR-29a could affect lipopolysaccharides (LPSs)-induced injury in human gingival …
A diagnostic model of polycystic ovary syndrome was constructed based on the genes associated with pyroptosis
X Chen, W Zhang, Y Ma, Y Chen, B Xu - 2023 - researchsquare.com
Background Polycystic ovary syndrome (PCOS) is a complex disease, and the underlying
mechanisms remain unclear. It has been suggested that genes involved in pyroptosis may …
mechanisms remain unclear. It has been suggested that genes involved in pyroptosis may …