Gene mutation is responsible for the development of hepatocellular carcinoma (HCC) with
hepatitis B virus (HBV) infection; however, the characteristics and associated biological …

Mutations in genes encoding key players in oncogenic signaling pathways trigger specific
downstream gene expression profiles in the respective tumor cell populations. While …

Summary ARID2 (ARID2), CTNNB1 (β catenin), tumor protein 53 (p53), and PIK3CA (p110α)
mutations are implicated in hepatocellular carcinoma (HCC); and previous work has …

The purpose of the study was to elucidate the anti-hepatoma effects and mechanisms of
Pogostemon cablin essential oils (PPa extract) in vitro and in vivo. PPa extract exhibited an …

The Wnt/β-catenin pathway is known to be frequently dysregulated in various human
malignancies. Alterations in the genes encoding the components of Wnt/β-catenin pathway …

Abstract Background Hepatitis C virus (HCV) was reported to relate to polymorphous and
frequent extrahepatic manifestation. Despite the limited studies, HCV viral oncoproteins may …

Hepatocellular carcinoma (HCC) is an aggressive gastrointestinal malignancy with a high
rate of mortality. Multiple studies have individually recognized members of RAP gene family …

This study aimed to elucidate the prognostic value of the leucine rich repeat containing 1
(LRRC1) gene in hepatocellular carcinoma (HCC) and to determine the effects of high and …

It has been estimated that 15%-20% of human cancers are attributable to infections, mostly
by carcinogenic viruses. The incidence varies worldwide, with a majority affecting …

Background Aging is a complex biological process accompanied by a time-dependent
functional decline that affects most living organisms. Omics studies help to comprehensively …