Endoplasmic reticulum stress and the unfolded protein response in cerebral ischemia/reperfusion injury
Ischemic stroke is an acute cerebrovascular disease characterized by sudden interruption of
blood flow in a certain part of the brain, leading to serious disability and death. At present …
blood flow in a certain part of the brain, leading to serious disability and death. At present …
[HTML][HTML] The role and therapeutic potential of nuclear factor κB (NF-κB) in ischemic stroke
G Xu, F Dong, L Su, ZX Tan, M Lei, L Li, D Wen… - Biomedicine & …, 2024 - Elsevier
Stroke is a prevalent cerebrovascular condition with a global impact, causing significant
rates of illness and death. Despite extensive research, the available treatment options for …
rates of illness and death. Despite extensive research, the available treatment options for …
Effects of spike protein and toxin-like peptides found in COVID-19 patients on human 3D neuronal/glial model undergoing differentiation: Possible implications for …
F Pistollato, M Petrillo, LA Clerbaux, G Leoni… - Reproductive …, 2022 - Elsevier
The possible neurodevelopmental consequences of SARS-CoV-2 infection are presently
unknown. In utero exposure to SARS-CoV-2 has been hypothesized to affect the developing …
unknown. In utero exposure to SARS-CoV-2 has been hypothesized to affect the developing …
[PDF][PDF] Dihydromyricetin attenuates cerebral ischemia reperfusion injury by inhibiting SPHK1/mTOR signaling and targeting ferroptosis
J Xie, T Zhang, P Li, D Wang, T Liu… - Drug design, development …, 2022 - Taylor & Francis
Background Dihydromyricetin (DHM) exerts protective effects in various brain diseases. The
aim of this research was to investigate the biological role of DHM in cerebral ischemia …
aim of this research was to investigate the biological role of DHM in cerebral ischemia …
The role of sphingolipids in endoplasmic reticulum stress
WJ Park, JW Park - FEBS letters, 2020 - Wiley Online Library
The endoplasmic reticulum (ER) is an important intracellular compartment in eukaryotic cells
and has diverse functions, including protein synthesis, protein folding, lipid metabolism and …
and has diverse functions, including protein synthesis, protein folding, lipid metabolism and …
[Retracted] Inhibition of SphK1/S1P Signaling Pathway Alleviates Fibrosis and Inflammation of Rat Myocardium after Myocardial Infarction
X Wu, J Xu, X Li, J Dai, L Wang - … and Mathematical Methods in …, 2022 - Wiley Online Library
Objective. The sphingosine kinase 1 (SphK1)/sphingosine‐1‐phosphate (S1P) signaling
pathway is involved in fibrosis and inflammatory responses of myocardial tissue after …
pathway is involved in fibrosis and inflammatory responses of myocardial tissue after …
ATF3 regulates SPHK1 in cardiomyocyte injury via endoplasmic reticulum stress
H Chen, S Luo, H Chen, C Zhang - Immunity, Inflammation and …, 2023 - Wiley Online Library
Aim Endoplasmic reticulum (ER) stress is common in different human pathologies, including
cardiac diseases. Sphingosine kinase‐1 (SPHK1) represents an important player in cardiac …
cardiac diseases. Sphingosine kinase‐1 (SPHK1) represents an important player in cardiac …
[HTML][HTML] PHLDA1 knockdown alleviates mitochondrial dysfunction and endoplasmic reticulum stress-induced neuronal apoptosis via activating PPARγ in cerebral …
Y Liu, H Zhao, N Chen, Y Li, Z Zheng, Z Sun… - Brain Research …, 2023 - Elsevier
Mitochondrial dysfunction and endoplasmic reticulum (ER) stress occur in ischemic stroke.
The disruption of these two organelles can directly lead to cell death through various …
The disruption of these two organelles can directly lead to cell death through various …