[HTML][HTML] Molecular mechanism of interaction between SARS-CoV-2 and host cells and interventional therapy
Q Zhang, R Xiang, S Huo, Y Zhou, S Jiang… - Signal transduction and …, 2021 - nature.com
The pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in an unprecedented setback …
syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in an unprecedented setback …
[HTML][HTML] Recent advances in management of COVID-19: A review
Abstract The coronavirus disease 2019 (COVID-19) pandemic caused and is still causing
significant mortality and economic consequences all over the globe. As of today, there are …
significant mortality and economic consequences all over the globe. As of today, there are …
[HTML][HTML] Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2
The SARS-CoV-2 virus is more transmissible than previous coronaviruses and causes a
more serious illness than influenza. The SARS-CoV-2 receptor binding domain (RBD) of the …
more serious illness than influenza. The SARS-CoV-2 receptor binding domain (RBD) of the …
The total number and mass of SARS-CoV-2 virions
Quantitatively describing the time course of the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection within an infected individual is important for …
coronavirus 2 (SARS-CoV-2) infection within an infected individual is important for …
[HTML][HTML] An alpaca nanobody neutralizes SARS-CoV-2 by blocking receptor interaction
L Hanke, L Vidakovics Perez, DJ Sheward… - Nature …, 2020 - nature.com
SARS-CoV-2 enters host cells through an interaction between the spike glycoprotein and
the angiotensin converting enzyme 2 (ACE2) receptor. Directly preventing this interaction …
the angiotensin converting enzyme 2 (ACE2) receptor. Directly preventing this interaction …
[HTML][HTML] mRNA-based SARS-CoV-2 vaccine candidate CVnCoV induces high levels of virus-neutralising antibodies and mediates protection in rodents
S Rauch, N Roth, K Schwendt, M Fotin-Mleczek… - npj Vaccines, 2021 - nature.com
Abstract mRNA technologies have recently proven clinical efficacy against coronavirus
disease 2019 and are among the most promising technologies to address the current …
disease 2019 and are among the most promising technologies to address the current …
Prospect of SARS-CoV-2 spike protein: Potential role in vaccine and therapeutic development
The recent outbreak of the betacoronavirus SARS-CoV-2 has become a significant concern
to public health care worldwide. As of August 19, 2020, more than 22,140,472 people are …
to public health care worldwide. As of August 19, 2020, more than 22,140,472 people are …
Nanobody cocktails potently neutralize SARS-CoV-2 D614G N501Y variant and protect mice
P Pymm, A Adair, LJ Chan… - Proceedings of the …, 2021 - National Acad Sciences
Neutralizing antibodies are important for immunity against SARS-CoV-2 and as therapeutics
for the prevention and treatment of COVID-19. Here, we identified high-affinity nanobodies …
for the prevention and treatment of COVID-19. Here, we identified high-affinity nanobodies …
[HTML][HTML] Receptor-binding domain-specific human neutralizing monoclonal antibodies against SARS-CoV and SARS-CoV-2
F Yu, R Xiang, X Deng, L Wang, Z Yu, S Tian… - … and Targeted Therapy, 2020 - nature.com
The outbreaks of severe acute respiratory syndrome (SARS) and Coronavirus Disease 2019
(COVID-19) caused by SARS-CoV and SARS-CoV-2, respectively, have posed severe …
(COVID-19) caused by SARS-CoV and SARS-CoV-2, respectively, have posed severe …
[HTML][HTML] Neutralizing antibodies for the treatment of COVID-19
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