[HTML][HTML] Nanobodies in the limelight: Multifunctional tools in the fight against viruses

A Moliner-Morro, GM McInerney… - Journal of General …, 2022 - microbiologyresearch.org
Antibodies are natural antivirals generated by the vertebrate immune system in response to
viral infection or vaccination. Unsurprisingly, they are also key molecules in the virologist's …

[HTML][HTML] Single domain antibodies derived from ancient animals as broadly neutralizing agents for SARS-CoV-2 and other coronaviruses

HT Lim, BH Kok, CP Lim, ABA Majeed, CY Leow… - Biomedical Engineering …, 2022 - Elsevier
With severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as an emergent
human virus since December 2019, the world population is susceptible to coronavirus …

[HTML][HTML] An overview of spike surface glycoprotein in severe acute respiratory syndrome–coronavirus

MK Kathiravan, S Radhakrishnan… - Frontiers in Molecular …, 2021 - frontiersin.org
The novel coronavirus originated in December 2019 in Hubei, China. This contagious
disease named as COVID-19 resulted in a massive expansion within 6 months by spreading …

Neutralizing monoclonal antibodies against highly pathogenic coronaviruses

R Xiang, Y Wang, L Wang, X Deng, S Huo… - Current Opinion in …, 2022 - Elsevier
The pandemic of Coronavirus Disease 2019 (COVID-19) caused by severe acute respiratory
syndrome 2 coronavirus (SARS-CoV-2) is a continuing worldwide threat to human health …

[HTML][HTML] Immunopathology, host-virus genome interactions, and effective vaccine development in SARS-CoV-2

DD Singh, I Han, EH Choi, DK Yadav - Computational and Structural …, 2020 - Elsevier
Coronaviruses are a group of enveloped RNA viruses that are diversely found in humans
and now declared a global pandemic by the World Health Organization in March 2020. The …

[HTML][HTML] Generation of HIV-resistant cells with a single-domain antibody: implications for HIV-1 gene therapy

H Jin, X Tang, L Li, Y Chen, Y Zhu, H Chong… - Cellular & Molecular …, 2021 - nature.com
The cure or functional cure of the “Berlin patient” and “London patient” indicates that infusion
of HIV-resistant cells could be a viable treatment strategy. Very recently, we genetically …

Unraveling the Dynamics of SARS-CoV-2 Mutations: Insights from Surface Plasmon Resonance Biosensor Kinetics

DT Nurrohman, NF Chiu - Biosensors, 2024 - mdpi.com
Surface Plasmon Resonance (SPR) technology is known to be a powerful tool for studying
biomolecular interactions because it offers real-time and label-free multiparameter analysis …

Coronavirus disease 2019 and the revival of passive immunization: Antibody therapy for inhibiting severe acute respiratory syndrome coronavirus 2 and preventing …

F Levi‐Schaffer, A de Marco - British Journal of Pharmacology, 2021 - Wiley Online Library
The coronavirus disease 2019 (COVID‐19) pandemic stimulated both the scientific
community and healthcare companies to undertake an unprecedented effort with the aim of …

Isolation, characterization, and structure-based engineering of a neutralizing nanobody against SARS-CoV-2

T Li, B Zhou, Y Li, S Huang, Z Luo, Y Zhou, Y Lai… - International Journal of …, 2022 - Elsevier
SARS-CoV-2 engages with human cells through the binding of its Spike receptor-binding
domain (S-RBD) to the receptor ACE2. Molecular blocking of this engagement represents a …

[HTML][HTML] Recent progress in the development of potential drugs against SARS-CoV-2

J Chen, F Ali, I Khan, YZ Zhu - Current Research in Pharmacology and …, 2021 - Elsevier
Abstract SARS-CoV-2, a newly emerged and highly pathogenic coronavirus, is identified as
the causal agent of Coronavirus Disease (2019)(COVID-19) in the late December 2019, in …