The role of aspirin and other platelet-active drugs in the treatment and prevention of
atherothrombosis has been reviewed recently by the Sixth American College of Chest …

Ventricular electrical storm (VES) is a clinical scenario characterized by the clustering of
multiple episodes of sustained ventricular arrhythmias (VA) over a short duration. Patients …

Objective: To determine the effects of antiplatelet therapy among patients at high risk of
occlusive vascular events. Design: Collaborative meta-analyses (systematic overviews) …

Background Despite improvements in the emergency treatment of myocardial infarction (MI),
early mortality and morbidity remain high. The antiplatelet agent clopidogrel adds to the …

Background A substantial proportion of patients receiving fibrinolytic therapy for myocardial
infarction with ST-segment elevation have inadequate reperfusion or reocclusion of the …

Background Despite previous randomised trials of early β-blocker therapy in the emergency
treatment of myocardial infarction (MI), uncertainty has persisted about the value of adding it …

Patients suffering a transient ischaemic attack (TIA) or ischaemic stroke (IS) have a high risk
of recurrence. The inhibition of platelet function is effective in the reduction of secondary …

We included 34 trials with 3742 participants, identified through 6 database and
supplementary searches (to May 2017): 29 were randomised; 4 were quasi‐randomised …

Background Cardiovascular disease is the number one cause of death globally. According
to the World Health Organization, 7.4 million people died from ischaemic heart diseases in …

OBJECTIVES: To review systematically the clinical effectiveness and the cost-effectiveness
of clopidogrel used in combination with standard therapy including aspirin, compared with …