Exploring animal models that resemble idiopathic pulmonary fibrosis

J Tashiro, GA Rubio, AH Limper, K Williams… - Frontiers in …, 2017 - frontiersin.org
Large multicenter clinical trials have led to two recently approved drugs for patients with
idiopathic pulmonary fibrosis (IPF); yet, both of these therapies only slow disease …

Lung cancer in patients with idiopathic pulmonary fibrosis

T Karampitsakos, V Tzilas, R Tringidou… - Pulmonary …, 2017 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a chronic fibrotic lung disease of unknown etiology.
With a gradually increasing worldwide prevalence and a mortality rate exceeding that of …

Therapeutic applications of mesenchymal stem cells in idiopathic pulmonary fibrosis

S Yang, P Liu, Y Jiang, Z Wang, H Dai… - Frontiers in Cell and …, 2021 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is an interstitial disease of unknown etiology
characterized by progressive pulmonary fibrosis. Pirfenidone and nintedanib are the only …

A systematic review of the role of dysfunctional wound healing in the pathogenesis and treatment of idiopathic pulmonary fibrosis

A Betensley, R Sharif, D Karamichos - Journal of clinical medicine, 2016 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive interstitial lung disorder
showcasing an interaction between genetic predisposition and environmental risks. This …

Mesenchymal stromal cells in animal bleomycin pulmonary fibrosis models: a systematic review

N Srour, B Thébaud - Stem cells translational medicine, 2015 - academic.oup.com
Idiopathic pulmonary fibrosis is an inexorably progressive lung disease with few available
treatments. New therapeutic options are needed. Stem cells have generated much …

PD-1/PD-L1 pathway mediates the alleviation of pulmonary fibrosis by human mesenchymal stem cells in humanized mice

K Ni, M Liu, J Zheng, L Wen, Q Chen… - American Journal of …, 2018 - atsjournals.org
Pulmonary fibrosis is a chronic progressive lung disease with few treatments. Human
mesenchymal stem cells (MSCs) have been shown to be beneficial in pulmonary fibrosis …

Mesenchymal stem cells for the treatment of idiopathic pulmonary fibrosis

A Tzouvelekis, R Toonkel, T Karampitsakos… - Frontiers in …, 2018 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is an inexorably progressive lung disease of unknown
origin. Prognosis is poor, with limited treatment options available, and the median survival …

Real-world experience with nintedanib in patients with idiopathic pulmonary fibrosis

E Brunnemer, J Wälscher, S Tenenbaum… - Respiration, 2018 - karger.com
Background: Nintedanib, an oral tyrosine kinase inhibitor, has been shown to slow down the
progression of idiopathic pulmonary fibrosis (IPF) in two randomised placebo-controlled …

[PDF][PDF] Overview of idiopathic pulmonary fibrosis (IPF) and evidence-based guidelines

R Sharif - Am J Manag Care, 2017 - ajmc.s3.amazonaws.com
OVERVIEW OF IPF AND EVIDENCE-BASED GUIDELINES of patients with a radiographic
and histopathologic pattern of usual interstitial pneumonia (UIP) and no other identifiable …

pH‐triggered aggregation of gold nanoparticles for enhanced labeling and long‐term CT imaging tracking of stem cells in pulmonary fibrosis treatment

C Yu, Z Chen, X Li, H Bao, Y Wang, B Zhang, J Huang… - Small, 2021 - Wiley Online Library
Gold nanoparticles (AuNPs) pose a great challenge in the development of nanotracers that
can self‐adaptively alter their properties in response to certain cellular environments for long …