Skeletal muscle is a crucial tissue for movement, gestural assistance, metabolic
homeostasis, and thermogenesis. It makes up approximately 40% of the total body weight …

Background Evidence regarding functional hypogonadism, previously referred to as 'late‐
onset'hypogonadism, has increased substantially during the last 10 year. Objective To …

Mendelian randomisation (MR) studies allow a better understanding of the causal effects of
modifiable exposures on health outcomes, but the published evidence is often hampered by …

The hypothalamic–pituitary–gonadal axis is of relevance in many processes related to the
development, maturation and ageing of the male. Through this axis, a cascade of …

Purpose To provide the evidence-based recommendations on the role of testosterone (T) on
age-related symptoms and signs remains. Methods The Italian Society of Andrology and …

Aims Observational studies show inconsistent associations of red meat consumption with
cardiovascular disease (CVD) and diabetes. Moreover, red meat consumption varies by sex …

Background: The influence of testosterone on risk for cardiovascular events in men is
uncertain. Previous observational studies of sex hormones and incident cardiovascular …

Alzheimer's disease is more prevalent in women, possibly due to sex or growth hormones
but existing evidence is inconclusive. We investigated whether genetically predicted sex and …

Background Sex hormone-binding globulin (SHBG), testosterone and oestradiol have been
associated with many diseases in observational studies; however, the causality of …

This narrative review discusses the current understanding, knowledge gaps and challenges
in expanding our knowledge of the association between menopause and the reproductive …