Impact of the Human Cell Atlas on medicine

JE Rood, A Maartens, A Hupalowska, SA Teichmann… - Nature medicine, 2022 - nature.com
Single-cell atlases promise to provide a 'missing link'between genes, diseases and
therapies. By identifying the specific cell types, states, programs and contexts where disease …

Novel research and future prospects of artificial intelligence in cancer diagnosis and treatment

C Zhang, J Xu, R Tang, J Yang, W Wang, X Yu… - Journal of Hematology & …, 2023 - Springer
Research into the potential benefits of artificial intelligence for comprehending the intricate
biology of cancer has grown as a result of the widespread use of deep learning and …

hist2RNA: An Efficient Deep Learning Architecture to Predict Gene Expression from Breast Cancer Histopathology Images

RK Mondol, EKA Millar, PH Graham, L Browne… - Cancers, 2023 - mdpi.com
Simple Summary Breast cancer diagnosis and treatment can be improved by understanding
the specific genetic makeup of a patient's tumour. Currently, this genetic information is …

Deep learning methodologies applied to digital pathology in prostate cancer: a systematic review

N Rabilloud, P Allaume, O Acosta, R De Crevoisier… - Diagnostics, 2023 - mdpi.com
Deep learning (DL), often called artificial intelligence (AI), has been increasingly used in
Pathology thanks to the use of scanners to digitize slides which allow us to visualize them on …

Harnessing artificial intelligence for prostate cancer management

L Zhu, J Pan, W Mou, L Deng, Y Zhu, Y Wang… - Cell Reports …, 2024 - cell.com
Prostate cancer (PCa) is a common malignancy in males. The pathology review of PCa is
crucial for clinical decision-making, but traditional pathology review is labor intensive and …

The ACROBAT 2022 challenge: automatic registration of breast cancer tissue

P Weitz, M Valkonen, L Solorzano, C Carr… - Medical Image …, 2024 - Elsevier
The alignment of tissue between histopathological whole-slide-images (WSI) is crucial for
research and clinical applications. Advances in computing, deep learning, and availability of …

Histopathological Image Classification with Cell Morphology Aware Deep Neural Networks

A Ignatov, J Yates, V Boeva - Proceedings of the IEEE/CVF …, 2024 - openaccess.thecvf.com
Histopathological images are widely used for the analysis of diseased (tumor) tissues and
patient treatment selection. While the majority of microscopy image processing was …

Towards computationally efficient prediction of molecular signatures from routine histology images

MW Lafarge, VH Koelzer - The Lancet Digital Health, 2021 - thelancet.com
Identification of actionable genomic alterations in diagnostic tissue samples provides key
information for personalised cancer treatment. However, current diagnostic tests used to …

An investigation of attention mechanisms in histopathology whole-slide-image analysis for regression objectives

P Weitz, Y Wang, J Hartman… - Proceedings of the …, 2021 - openaccess.thecvf.com
Abstract Analysis of whole-slide-images (WSIs) of histopathology tissue sections remains
challenging due to the gigapixel scale of these images, which often necessitates their …

Clinical evaluation of deep learning-based risk profiling in breast cancer histopathology and comparison to an established multigene assay

Y Wang, W Sun, E Karlsson, S Kang Lövgren… - Breast Cancer Research …, 2024 - Springer
Purpose To evaluate the Stratipath Breast tool for image-based risk profiling and compare it
with an established prognostic multigene assay for risk profiling in a real-world case series …