F Schreibing, R Kramann - Nature Reviews Nephrology, 2022 - nature.com
The field of single-cell genomics and spatial technologies is rapidly evolving and has already provided unprecedented insights into complex tissues. Major advances have been …
Y Nihei, H Suzuki, Y Suzuki - Frontiers in Immunology, 2023 - frontiersin.org
Immunoglobulin A (IgA) is the most abundant isotype of antibodies, provides a first line of defense at mucosal surfaces against pathogens, and thereby contributes to mucosal …
MJ Moeller, R Kramann, T Lammers, B Hoppe… - Frontiers in …, 2022 - frontiersin.org
Organ fibrogenesis is characterized by a common pathophysiological final pathway independent of the underlying progressive disease of the respective organ. This makes it …
L Zeng, K Yang, T Zhang, X Zhu, W Hao, H Chen… - Journal of …, 2022 - Elsevier
Autoimmunity refers to the phenomenon that the body's immune system produces antibodies or sensitized lymphocytes to its own tissues to cause an immune response. Immune …
The kidney contains a population of resident macrophages from birth that expands as it grows and forms a contiguous network throughout the tissue. Kidney-resident macrophages …
J Xu, C Shen, W Lin, T Meng, JD Ooi… - Frontiers in …, 2021 - frontiersin.org
Idiopathic membranous nephropathy (IMN) is an organ-specific autoimmune disease of the kidney glomerulus. It may gradually progress to end-stage renal disease (ESRD) …
The deposition of immune complexes, activation of complement and infiltration of the kidney by cells of the adaptive and innate immune systems have long been considered responsible …
R Abedini-Nassab, N Sadeghidelouei… - Analytica Chimica …, 2023 - Elsevier
Lab-on-a-chip tools have played a pivotal role in advancing modern biology and medicine. A key goal in this field is to precisely transport single particles and cells to specific locations …
The growing availability of single-cell data has sparked an increased interest in the inference of cell-cell communication from this data. Many tools have been developed for this …