CDKL5 deficiency disorder (CDD) is an X-linked brain disorder of young children and is
caused by pathogenic variants in the cyclin-dependent kinase-like 5 (CDKL5) gene …

Rett syndrome (RTT) and CDKL5 deficiency disorder (CDD) are two rare X-linked
developmental brain disorders with overlapping but distinct phenotypic features. This review …

Early-onset epileptic encephalopathies are severe disorders often associated with specific
genetic mutations. In this context, the CDKL5 deficiency disorder (CDD) is a …

CDKL5 deficiency disorder (CDD), a rare and severe neurodevelopmental disease caused
by mutations in the X-linked CDKL 5 gene, is characterized by early-onset epilepsy …

Background CDKL5 deficiency disorder (CDD), a severe neurodevelopmental disorder
characterized by early onset epilepsy, intellectual disability, and autistic features, is caused …

Cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder (CDD) is a rare
neurodevelopmental disease caused by mutations in the X-linked CDKL5 gene. CDD is …

CDKL5 deficiency disorder (CDD) is a rare X-linked neurodevelopmental disorder that is
characterised by early-onset seizures, intellectual disability, gross motor impairment, and …

Ras‐related C3 botulinum toxin substrate 1 (Rac1) is a small GTPase that is well known for
its sensitivity to the environmental stress of a cell or an organism. It senses the external …

Cyclin‐dependent kinase‐like 5 (CDKL5, also known as STK9) is a serine/threonine protein
kinase originally identified in 1998 during a transcriptional mapping project of the human X …

Mutations in the X-linked cyclin-dependent kinase-like 5 (CDKL5) gene cause a rare
neurodevelopmental disorder characterized by early-onset seizures and severe cognitive …